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波兰人群中PLG组系统的群体研究。

Population studies on PLG group system in the Polish population.

作者信息

Schlesinger D, Mańczak M, Hałasa J

出版信息

Arch Immunol Ther Exp (Warsz). 1985;33(5):617-20.

PMID:3834881
Abstract

Distribution of PLG types was studied in a sample of the Polish population numbering 230 subjects by the method of high-voltage agarose electrophoresis. Of three phenotypes encountered, PLG1, appeared with the frequency of 0.4870, PLG2-1 with 0.4391 and PLG2 with 0.0739. Assuming the hypothesis of PLG controlled by 2 alleles the frequencies of genotypes were calculated as follows: for PLG1 gene -0.71 and for PLG2 gene -0.29. PLG system in the Polish population was confirmed to be in a state of genetic equilibrium. The frequencies of PLG genes in the Polish population do not deviate from the frequencies encountered in other European populations.

摘要

通过高压琼脂糖电泳法,对230名波兰人群样本中的纤溶酶原(PLG)类型分布进行了研究。在观察到的三种表型中,PLG1的出现频率为0.4870,PLG2 - 1为0.4391,PLG2为0.0739。假设PLG由两个等位基因控制,计算出的基因型频率如下:PLG1基因频率为0.71,PLG2基因频率为0.29。证实波兰人群中的PLG系统处于遗传平衡状态。波兰人群中PLG基因的频率与其他欧洲人群中观察到的频率没有偏差。

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