Li Fanlin, Zheng Ying, Yang Fan, Liu Jianhong
Department of Gynecologic Oncology, West China Second Hospital, Sichuan University, and Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Front Oncol. 2024 Feb 1;14:1337719. doi: 10.3389/fonc.2024.1337719. eCollection 2024.
Applying transumbilical laparoendoscopic single-site surgery to endometrial cancers is worldwide, and the depiction of the learning curve is rarely described, which leads to the vagueness of young clinical practitioners. We accumulated the data to identify the completion of the learning curve by analyzing the operative and postoperative outcomes of the patients with endometrial cancer for transumbilical laparoendoscopic single-site surgery (TU-LESS).
This was a retrospective, consecutive single-center study of patients with endometrial cancer undergoing standard endometrial cancer comprehensive staging surgery (extrafascial hysterectomy, bilateral salpingectomy, and pelvic lymphadenectomy) through TU-LESS by an experienced surgeon from December, 2017 to June, 2021 in the Department of Gynecologic Oncology, West China Second Hospital, Sichuan University, China.
After applying the inclusion and exclusion criteria, 42 patients were included in the study. The learning curve for this study was evaluated using both cumulative sum (CUSUM) and risk-adjusted CUSUM (RA-CUSUM) methods. Applying CUSUM and RA-CUSUM has grouped 42 cases into three phases. The prior five cases represented the learning period. The following six cases were needed to lay a technical foundation (cases 6-11). The third phase was regarded as achieving proficiency (cases 12-42). The operative time decreased drastically with the learning curve. There were no significant differences in terms of postoperative complications and lymph node retrieval among the three phases. More difficult patients were confronted in the third phase.
In our study, the learning curve was composed of three phases. According to the results of our study, 11 cases were required for experienced surgeons to achieve a technical foundation.
经脐单孔腹腔镜手术应用于子宫内膜癌的治疗在全球范围内开展,但关于学习曲线的描述却很少,这使得年轻临床医生对此认识模糊。我们通过分析子宫内膜癌患者经脐单孔腹腔镜手术(TU-LESS)的手术及术后结果来积累数据,以确定学习曲线的完成情况。
这是一项回顾性、连续性单中心研究,研究对象为2017年12月至2021年6月在中国四川大学华西第二医院妇科肿瘤科任有经验的外科医生通过TU-LESS为子宫内膜癌患者实施标准子宫内膜癌全面分期手术(筋膜外子宫切除术、双侧输卵管切除术和盆腔淋巴结清扫术)。
应用纳入和排除标准后,42例患者纳入研究。本研究的学习曲线采用累积和(CUSUM)及风险调整累积和(RA-CUSUM)方法进行评估。应用CUSUM和RA-CUSUM将42例病例分为三个阶段。前5例代表学习期。接下来6例用于奠定技术基础(第6 - 11例)。第三阶段视为熟练期(第12 - 42例)。随着学习曲线的进展,手术时间大幅下降。三个阶段在术后并发症和淋巴结获取方面无显著差异。第三阶段遇到的患者病情更复杂。
在我们的研究中,学习曲线由三个阶段组成。根据我们的研究结果,经验丰富的外科医生需要11例手术来奠定技术基础。