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新型椎体钛多孔微型钢板的生物力学评价及颈椎开门式椎板成形术与椎板切除术的力学比较:有限元分析

Biomechanical evaluation on a new type of vertebral titanium porous mini-plate and mechanical comparison between cervical open-door laminoplasty and laminectomy: a finite element analysis.

作者信息

Lin Zhiwei, Lin Dongxin, Xu Lin, Chen Qiwei, Vashisth Manoj Kumar, Huang Xuecheng, Deng Yuping, Zhang Feihu, Huang Wenhua

机构信息

School of Basic Medical Sciences, Guangdong Medical University, Dongguan, China.

Guangdong Provincial Key Laboratory of Digital Medicine and Biomechanics, National Key Discipline of Human Anatomy, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

出版信息

Front Bioeng Biotechnol. 2024 Feb 5;12:1353797. doi: 10.3389/fbioe.2024.1353797. eCollection 2024.

Abstract

Compare the spine's stability after laminectomy (LN) and laminoplasty (LP) for two posterior surgeries. Simultaneously, design a new vertebral titanium porous mini plate (TPMP) to achieve firm fixation of the open-door vertebral LP fully. The objective is to enhance the fixation stability, effectively prevent the possibility of "re-closure," and may facilitate bone healing. TPMP was designed by incorporating a fusion body and porous structures, and a three-dimensional finite element cervical model of C2-T1 was constructed and validated. Load LN and LP finite element models, respectively, and analyze and simulate the detailed processes of the two surgeries. It was simultaneously implanting the TPMP into LP to evaluate its biomechanical properties. We find that the range of motion (ROM) of C4-C5 after LN surgery was greater than that of LP implanted with different plates alone. Furthermore, flexion-extension, lateral bending, and axial rotation reflect this change. More noteworthy is that LN has a much larger ROM on C2-C3 in axial rotation. The ROM of LP implanted with two different plates is similar. There is almost no difference in facet joint stress in lateral bending. The facet joint stress of LN is smaller on C2-C3 and C4-C5, and larger more prominent on C5-C6 in the flexion-extension. Regarding intervertebral disc pressure (IDP), there is little difference between different surgeries except for the LN on C2-C3 in axial rotation. The plate displacement specificity does not significantly differ from LP with vertebral titanium mini-plate (TMP) and LP with TPMP after surgery. The stress of LP with TPMP is larger in C4-C5, C5-C6. Moreover, LP with TMP shows greater stress in the C3-C4 during flexion-extension and lateral bending. LP may have better postoperative stability when posterior approach surgery is used to treat CSM; at the same time, the new type of vertebral titanium mini-plate can achieve almost the same effect as the traditional titanium mini-plate after surgery for LP. In addition, it has specific potential due to the porous structure promoting bone fusion.

摘要

比较两种后路手术——椎板切除术(LN)和椎板成形术(LP)后脊柱的稳定性。同时,设计一种新型椎体钛多孔微型钢板(TPMP),以实现开门式椎体LP的牢固固定。目的是提高固定稳定性,有效防止“再闭合”的可能性,并可能促进骨愈合。TPMP通过融合体和多孔结构设计而成,并构建并验证了C2-T1的三维有限元颈椎模型。分别加载LN和LP有限元模型,分析和模拟两种手术的详细过程。同时将TPMP植入LP以评估其生物力学性能。我们发现,LN手术后C4-C5的活动范围(ROM)大于单独植入不同钢板的LP。此外,屈伸、侧弯和轴向旋转均反映了这种变化。更值得注意的是,LN在C2-C3的轴向旋转中ROM要大得多。植入两种不同钢板的LP的ROM相似。侧弯时小关节应力几乎没有差异。LN在C2-C3和C4-C5的小关节应力较小,在屈伸时C5-C6处更大更明显。关于椎间盘压力(IDP),除了C2-C3轴向旋转时的LN外,不同手术之间几乎没有差异。术后钢板位移特异性与椎体钛微型钢板(TMP)的LP和TPMP的LP没有显著差异。TPMP的LP在C4-C5、C5-C6处应力较大。此外,TMP的LP在屈伸和侧弯时C3-C4处应力更大。当采用后路手术治疗脊髓型颈椎病(CSM)时,LP术后可能具有更好的稳定性;同时,新型椎体钛微型钢板在LP手术后可达到与传统钛微型钢板几乎相同的效果。此外,由于多孔结构促进骨融合,它具有特定的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6b1/10875091/025c6912aa12/fbioe-12-1353797-g001.jpg

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