一例罕见的高钙血症型卵巢小细胞癌。

A rare case of small cell carcinoma of the ovary, hypercalcemic type.

作者信息

Boujida Ismail, Mahdi Y, Khmou M, Ech-Charif S, Horache K, El-Aoufir O, Gamra L, El-Khannoussi B

机构信息

Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center, Rabat 10100, Morocco.

Faculty of Medicine and Pharmacy, Mohammed 5 University, Rabat 10100, Morocco.

出版信息

J Surg Case Rep. 2024 Feb 21;2024(2):rjae079. doi: 10.1093/jscr/rjae079. eCollection 2024 Feb.

DOI:10.1093/jscr/rjae079

PMID:38389514

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10881294/

Abstract

Small cell carcinoma of ovary, hypercalcemic type (SCCOHT) is an unusual malignant tumor that most commonly affects young women. Unfortunately, it has a very poor prognosis. We describe here an unusual case of a Moroccan young woman with a left ovarian mass and a symptomatic hypercalcemia. Morphologically, there are some malignant tumors that resemble SCCOHT; thus, it is very challenging to diagnose, and immunohistochemistry has a great contribution in it. Hopefully, molecular tools and new therapies will improve the management of these cases in the near future.

摘要

卵巢小细胞癌，高钙血症型（SCCOHT）是一种罕见的恶性肿瘤，最常影响年轻女性。不幸的是，其预后非常差。我们在此描述一例不寻常的病例，一名摩洛哥年轻女性患有左侧卵巢肿块并伴有症状性高钙血症。在形态学上，有一些恶性肿瘤类似于SCCOHT；因此，诊断极具挑战性，免疫组织化学在其中有很大作用。有望在不久的将来，分子工具和新疗法能改善这些病例的治疗。