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过去50年国际麻醉品研究会议对阿片类药物研究的贡献。

Contributions of the International Narcotics Research Conference to Opioid Research Over the Past 50 years.

作者信息

Cox Brian M, Toll Lawrence

机构信息

Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

Department of Biomedical Sciences, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, United States.

出版信息

Adv Drug Alcohol Res. 2022 Feb 18;2:10115. doi: 10.3389/adar.2022.10115. eCollection 2022.

Abstract

The International Narcotics Research Conference (INRC), founded in 1969, has been a successful forum for research into the actions of opiates, with an annual conference since 1971. Every year, scientists from around the world have congregated to present the latest data on novel opiates, opiate receptors and endogenous ligands, mechanisms of analgesic activity and unwanted side effects, etc. All the important discoveries in the opiate field were discussed, often first, at the annual INRC meeting. With an apology to important events and participants not discussed, this review presents a short history of INRC with a discussion of groundbreaking discoveries in the opiate field and the researchers who presented from the first meeting up to the present.

摘要

国际麻醉品研究会议(INRC)成立于1969年,自1971年起每年举办一次会议,一直是研究阿片类药物作用的成功论坛。每年,来自世界各地的科学家齐聚一堂,展示关于新型阿片类药物、阿片受体和内源性配体、镇痛活性机制和不良副作用等方面的最新数据。阿片类药物领域的所有重要发现通常都是在INRC年度会议上首次进行讨论的。在此,对于未讨论的重要事件和参与者表示歉意,本综述简要介绍了INRC的历史,并讨论了阿片类药物领域的突破性发现以及从第一次会议至今的参会研究人员。

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