入住重症监护病房的新冠肺炎孕妇：与未感染新冠肺炎的重症孕妇历史队列的比较。
Pregnant Patients with COVID-19 Admitted to an ICU: A Comparison with a Historical Cohort of Critical Pregnant Patients without COVID-19.
作者信息
Iacovazzo Carmine, Capasso Letizia, Visani Carola, Salomè Serena, Vargas Maria
机构信息
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80100 Naples, Italy.
Department of Translational Medical Sciences, Division of Neonatology, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy.
出版信息
Life (Basel). 2024 Jan 23;14(2):165. doi: 10.3390/life14020165.
AIM OF THE STUDY
Maternal mortality and ICU admissions have increased during the COVID-19 pandemic. We reported a case-series of pregnant patients with COVID-19 admitted to an ICU and we compared them with a historical cohort of pregnant patients admitted to an ICU without COVID-19.
METHODS
We included all pregnant patients with laboratory-confirmed COVID-19 infection admitted to our ICU in 2021. As a historical control group, we included all pregnant women who were admitted to our ICU between 1 January 2008 and 31 December 2013.
RESULTS
In 2021, 11 pregnant patients (pts) with COVID-19 were admitted to an ICU, representing 2.87% of ICU admissions. We found that pregnant patients with COVID-19 (1) had a higher BMI (34.6 vs. 28.8, = 0.04) and a lower gestational age (30.6 vs. 34 weeks, = 0.03), (2) were mainly admitted for respiratory failure (100% vs. 2.7%; = 0.001) and (3) required more days of invasive and non-invasive ventilations (54.5% vs. 5.2%, = 0.002), a longer duration of stay at the ICU (21.9 vs. 4.8 days, < 0.0001) and had a higher mortality rate (27.3% vs. 0%, = 0.0192).
CONCLUSIONS
Pregnant patients with COVID-19 represent a challenge for ICU physicians due to their different characteristics and outcomes when compared to pregnant patients without COVID-19.
研究目的
在新冠疫情期间，孕产妇死亡率和入住重症监护病房（ICU）的人数有所增加。我们报告了一系列入住ICU的新冠病毒感染孕妇病例，并将她们与历史队列中入住ICU但未感染新冠病毒的孕妇进行了比较。
方法
我们纳入了2021年入住我院ICU且实验室确诊感染新冠病毒的所有孕妇。作为历史对照组，我们纳入了2008年1月1日至2013年12月31日期间入住我院ICU的所有孕妇。
结果
2021年，11例感染新冠病毒的孕妇入住ICU，占ICU入院人数的2.87%。我们发现，感染新冠病毒的孕妇（1）体重指数（BMI）较高（34.6 vs. 28.8，P = 0.04），孕周较低（30.6 vs. 34周，P = 0.03）；（2）主要因呼吸衰竭入院（100% vs. 2.7%；P = 0.001）；（3）需要更多天数的有创和无创通气（54.5% vs. 5.2%，P = 0.002），在ICU的住院时间更长（21.9 vs. 4.8天，P < 0.0001），死亡率更高（27.3% vs. 0%，P = 0.0192）。
结论
与未感染新冠病毒的孕妇相比，感染新冠病毒的孕妇因其不同的特征和结局，给ICU医生带来了挑战。
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