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在线自适应磁共振引导放射治疗中临床并行工作流程的评估:治疗时段时间的详细评估

Evaluation of clinical parallel workflow in online adaptive MR-guided Radiotherapy: A detailed assessment of treatment session times.

作者信息

Votta Claudio, Iacovone Sara, Turco Gabriele, Carrozzo Valerio, Vagni Marica, Scalia Aurora, Chiloiro Giuditta, Meffe Guenda, Nardini Matteo, Panza Giulia, Placidi Lorenzo, Romano Angela, Cornacchione Patrizia, Gambacorta Maria Antonietta, Boldrini Luca

机构信息

Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Roma, Italy.

Università Cattolica del Sacro Cuore, Roma, Italy.

出版信息

Tech Innov Patient Support Radiat Oncol. 2024 Feb 13;29:100239. doi: 10.1016/j.tipsro.2024.100239. eCollection 2024 Mar.

Abstract

INTRODUCTION

Advancements in MRI-guided radiotherapy (MRgRT) enable clinical parallel workflows (CPW) for online adaptive planning (oART), allowing medical physicists (MPs), physicians (MDs), and radiation therapists (RTTs) to perform their tasks simultaneously. This study evaluates the impact of this upgrade on the total treatment time by analyzing each step of the current 0.35T-MRgRT workflow.

METHODS

The time process of the workflow steps for 254 treatment fractions in 0.35 MRgRT was examined. Patients have been grouped based on disease site, breathing modality (BM) (BHI or FB), and fractionation (stereotactic body RT [SBRT] or standard fractionated long course [LC]). The time spent for the following workflow steps in Adaptive Treatment (ADP) was analyzed: Patient Setup Time (PSt), MRI Acquisition and Matching (MRt), MR Re-contouring Time (RCt), Re-Planning Time (RPt), Treatment Delivery Time (TDt). Also analyzed was the timing of treatments that followed a Simple workflow (SMP), without the online re-planning (PSt + MRt + TDt.).

RESULTS

The time analysis revealed that the ADP workflow (median: 34 min) is significantly (p < 0.05) longer than the SMP workflow (19 min). The time required for ADP treatments is significantly influenced by TDt, constituting 40 % of the total time. The oART steps (RCt + RPt) took 11 min (median), representing 27 % of the entire procedure. Overall, 79.2 % of oART fractions were completed in less than 45 min, and 30.6 % were completed in less than 30 min.

CONCLUSION

This preliminary analysis, along with the comparative assessment against existing literature, underscores the potential of CPW to diminish the overall treatment duration in MRgRT-oART. Additionally, it suggests the potential for CPW to promote a more integrated multidisciplinary approach in the execution of oART.

摘要

引言

磁共振成像引导放疗(MRgRT)技术的进步使得在线自适应放疗(oART)的临床并行工作流程(CPW)成为可能,这使得医学物理师(MP)、医生(MD)和放射治疗师(RTT)能够同时执行各自的任务。本研究通过分析当前0.35T-MRgRT工作流程的每个步骤,评估了这一升级对总治疗时间的影响。

方法

对0.35T MRgRT中254个治疗分次的工作流程步骤的时间过程进行了检查。患者根据疾病部位、呼吸方式(BM)(屏气或自由呼吸)和分割方式(立体定向体部放疗[SBRT]或标准分割长疗程[LC])进行分组。分析了自适应治疗(ADP)中以下工作流程步骤所花费的时间:患者摆位时间(PSt)、磁共振成像采集与匹配(MRt)、磁共振重新轮廓勾画时间(RCt)、重新计划时间(RPt)、治疗交付时间(TDt)。还分析了采用简单工作流程(SMP)且无在线重新计划的治疗时间(PSt + MRt + TDt)。

结果

时间分析显示,ADP工作流程(中位数:34分钟)明显长于SMP工作流程(19分钟)(p < 0.05)。ADP治疗所需时间受TDt显著影响,占总时间的40%。oART步骤(RCt + RPt)耗时11分钟(中位数),占整个过程的27%。总体而言,79.2%的oART分次在45分钟内完成,30.6%在30分钟内完成。

结论

这一初步分析以及与现有文献的比较评估强调了CPW在缩短MRgRT-oART总体治疗时长方面的潜力。此外,这表明CPW在oART实施过程中促进更综合的多学科方法的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a714/10883837/6f7151e46a61/gr1.jpg

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