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颈动脉中贫血、糖尿病及健康血流的血液动力学行为分析

Hemodynamical behavior analysis of anemic, diabetic, and healthy blood flow in the carotid artery.

作者信息

Ahmed Hashnayne, Podder Chinmayee

机构信息

Department of Mathematics, Faculty of Science & Engineering, University of Barishal, Barishal, 8200, Bangladesh.

Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL, 32611, USA.

出版信息

Heliyon. 2024 Feb 18;10(4):e26622. doi: 10.1016/j.heliyon.2024.e26622. eCollection 2024 Feb 29.

Abstract

The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through the carotid artery, which is divided into internal and exterior parts with a decreased radius. The blood flow was classified as basic pulsatile to simulate the human heart's rhythmic pulses. For hemodynamic modeling viscosity of the fluid, the Carreau model was utilized with four distinct blood instances: Anemic, diabetic, and two healthy blood types. The boundary conditions with Carreau viscosity were applied using the Ansys Fluent simulator, and the governing equations were solved using the finite volume technique. Different time steps were tested for their impact on wall deformation, strain rate, blood velocity, pressure, wall shear, and skin friction coefficient. The hemodynamical parameters were calculated using many cross-sectional planes along the artery. Finally, the impact of the four types of blood cases listed above was investigated, and we discovered that each blood case has a substantial impact on blood velocity, pressure, wall shear, and strain rate along the artery.

摘要

利用计算流体动力学研究血液流变学对通过人体颈动脉的血流动力学参数的影响。我们进行了三维建模和模拟,以研究通过颈动脉的血流,颈动脉分为内径减小的内部和外部部分。血流被分类为基本脉动,以模拟人类心脏的有节奏脉搏。对于流体动力学建模中的流体粘度,使用Carreau模型并针对四种不同的血液情况:贫血、糖尿病和两种健康血型。使用Ansys Fluent模拟器应用具有Carreau粘度的边界条件,并使用有限体积技术求解控制方程。测试了不同时间步长对壁变形、应变率、血流速度、压力、壁面切应力和皮肤摩擦系数的影响。沿着动脉使用多个横截面计算血流动力学参数。最后,研究了上述四种血液情况的影响,我们发现每种血液情况对动脉沿线的血流速度、压力、壁面切应力和应变率都有重大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7d6/10900792/7eafd5b73cff/gr1.jpg

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