Department of Epidemiology, Ministry of Education Key Laboratory of Public Health Safety (Fudan University), School of Public Health, Fudan University, Shanghai 200032, China.
Institute of Immunization Planning, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
Vaccine. 2024 Apr 2;42(9):2246-2253. doi: 10.1016/j.vaccine.2024.02.076. Epub 2024 Feb 29.
Increasing countries are expanding the human papillomavirus (HPV) vaccination to men, which has not yet been licensed in China. This study investigated the parental willingness to accept (WTA) and pay (WTP) HPV vaccine for their sons aged 9-14.
In Shanghai, a metropolis area of China, parents with boys aged 9-14 were recruited to complete an online questionnaire using a convenience sampling strategy. Parental WTA were determined for parents themselves and for their sons. Parental preference of HPV vaccine was measured using discrete choice experiment in two assumed government subsidy scenarios that referred to HPV vaccination subsidy mechanisms for girls in China. Additionally, parental WTP was estimated using contingent valuation method.
A total of 2493 parents with boys aged 9-14 were included in the study. Majority of mothers (88.99 % and 90.99 %) and fathers (79.57 % and 85.04 %) showed WTA HPV vaccine for themselves and sons, respectively. Parental gender, age, monthly household income, knowledge, and awareness were positively associated with parental WTA for their sons (each P < 0.05). Remarkably, more mothers showed specific preference of HPV vaccine for themselves (53.67 %) and sons (47.78 %), while more fathers showed no preference for themselves (46.76 %) and sons (53.81 %). In the two assumed government subsidy scenarios, parents mostly preferred domestic HPV vaccines for themselves and sons (each P < 0.05). Additionally, mothers had significantly higher WTP for sons (mean value, 2122.75 CNY) than fathers did (1695.40 CNY) (P < 0.001). However, parental WTP was similar between for themselves and for sons, regardless of mothers and fathers (each P > 0.05).
Parents have high WTA and WTP HPV vaccine for boys aged 9-14 in Shanghai, which may provide evidence for preparing HPV vaccination strategy. Acceptance of HPV vaccines and roll-out in boys could be enhanced through the availability of government subsidy mechanism and domestic HPV vaccines.
越来越多的国家正在扩大 HPV 疫苗接种范围，包括男性，但中国尚未批准。本研究旨在调查父母对 9-14 岁男孩 HPV 疫苗的接种意愿和付费意愿。
在上海这个中国大都市地区，采用便利抽样策略，招募了 9-14 岁男孩的父母完成在线问卷。通过离散选择实验，在两种假设的政府补贴方案下，分别评估了父母对 HPV 疫苗的偏好。其中，HPV 疫苗接种补贴机制参考了中国女性 HPV 疫苗接种补贴机制。此外，还采用了条件价值评估法来评估父母的支付意愿。
共有 2493 名 9-14 岁男孩的父母参与了本研究。大多数母亲（88.99%和 90.99%）和父亲（79.57%和 85.04%）表示愿意为自己和儿子接种 HPV 疫苗。父母的性别、年龄、家庭月收入、知识和意识与父母对儿子的接种意愿呈正相关（均 P<0.05）。值得注意的是，更多的母亲对自己（53.67%）和儿子（47.78%）接种 HPV 疫苗表示明确偏好，而更多的父亲对自己（46.76%）和儿子（53.81%）接种 HPV 疫苗表示无偏好。在两种假设的政府补贴方案下，父母更倾向于为自己和儿子接种国产 HPV 疫苗（均 P<0.05）。此外，母亲对儿子的支付意愿（2122.75 元）明显高于父亲（1695.40 元）（P<0.001）。然而，无论母亲还是父亲，他们对自己和儿子的 HPV 疫苗接种意愿的支付意愿都相似（均 P>0.05）。
上海的父母对 9-14 岁男孩接种 HPV 疫苗具有较高的接种意愿和付费意愿，这可能为制定 HPV 疫苗接种策略提供依据。通过提供政府补贴机制和国产 HPV 疫苗，可提高家长对 HPV 疫苗的接受程度，促进 HPV 疫苗在男孩中的推广。
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