格鲁吉亚丙型肝炎感染、治疗状况与 2019 冠状病毒病相关住院之间的关系。
Relationship Between Hepatitis C Infection and Treatment Status and Coronavirus Disease 2019-Related Hospitalizations in Georgia.
机构信息
Department of Community Medicine, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Department of Medical Statistics, National Center for Disease Control and Public Health Georgia, Tbilisi, Georgia.
出版信息
J Infect Dis. 2024 Sep 23;230(3):e694-e699. doi: 10.1093/infdis/jiae103.
BACKGROUND
The aim of this study was to evaluate the impact of hepatitis C virus (HCV) infection and treatment status on coronavirus disease 2019 (COVID-19)-related hospitalizations in Georgia.
METHODS
We analyzed 2020-2021 Georgian health registry data for COVID-19-positive individuals and categorized the data by HCV infection and treatment status. Logistic regression was used to assess the strengths of the associations.
RESULTS
Treated individuals with HCV had lower odds of COVID-19-related hospitalization compared to anti-HCV-negative individuals, while untreated HCV-viremic and anti-HCV-positive nonviremic individuals had higher odds.
CONCLUSIONS
HCV treatment prior to COVID-19 infection was associated with lower odds of COVID-19-related hospitalization, highlighting the benefits of HCV management in the context of the pandemic.
背景
本研究旨在评估丙型肝炎病毒（HCV）感染和治疗状况对格鲁吉亚 2019 冠状病毒病（COVID-19）相关住院的影响。
方法
我们分析了 2020-2021 年格鲁吉亚健康登记数据中 COVID-19 阳性个体，并按 HCV 感染和治疗状况对数据进行分类。采用 logistic 回归评估关联强度。
结果
与抗 HCV 阴性个体相比，接受 HCV 治疗的个体 COVID-19 相关住院的可能性较低，而未接受治疗的 HCV 病毒血症和抗 HCV 阳性非病毒血症个体的可能性较高。
结论
COVID-19 感染前的 HCV 治疗与 COVID-19 相关住院的可能性降低相关，突出了在大流行背景下 HCV 管理的益处。
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