Virginia Commonwealth University Health System, Richmond, VA, USA.
Central Virginia Veterans Affairs Health Care System, Richmond, VA, USA.
Spinal Cord Ser Cases. 2024 Mar 4;10(1):8. doi: 10.1038/s41394-024-00623-8.
Patients with spinal cord injuries/disorders (SCI/D) often suffer from bladder dysfunction, commonly referred to as neurogenic bladder or neurogenic lower urinary tract dysfunction (NLUTD). Standard urologic evaluation and management help to minimize complications such as vesicoureteral reflux, urinary tract infection, and nephrolithiasis. However, we have further encountered patients with more complex issues, such as chronic kidney disease (CKD), end-stage renal disease (ESRD), bilateral nephrectomies, and urinary diversion/augmentation surgeries. Of particular interest, there is a lack of standardized guidance for bladder management in SCI/D patients with ESRD. These patients are at high risk for urological complications and would benefit from codified bladder management strategies.
In this article, we present eleven unique cases of NLUTD with associated ESRD and discuss recommendations utilizing simple and commonly available clinical interventions.
The inherently small population size of SCI/D patients with NLUTD and ESRD makes detailing a large sample size case series difficult. Future studies must aim to include a larger sample size as able, however, to better determine standardized protocols for chronic bladder management in SCI/D patients with NLUTD and ESRD. Experiences from this small case series are offered for consideration.
脊髓损伤/疾病(SCI/D)患者常伴有膀胱功能障碍,通常称为神经性膀胱或神经性下尿路功能障碍(NLUTD)。标准泌尿科评估和管理有助于最大限度地减少膀胱输尿管反流、尿路感染和肾结石等并发症。然而,我们还遇到了更多复杂问题的患者,如慢性肾脏病(CKD)、终末期肾病(ESRD)、双侧肾切除术以及尿路转流/增强手术。特别值得注意的是,ESRD 的 SCI/D 患者的膀胱管理缺乏标准化指导。这些患者存在高泌尿道并发症风险,需要制定规范的膀胱管理策略。
本文介绍了 11 例 NLUTD 伴 ESRD 的独特病例,并讨论了利用简单且常用的临床干预措施的建议。
NLUTD 和 ESRD 的 SCI/D 患者的固有人口规模较小,因此详细说明大样本量病例系列较为困难。未来的研究必须旨在纳入更大的样本量,以便更好地确定 NLUTD 和 ESRD 的 SCI/D 患者慢性膀胱管理的标准化方案。本小型病例系列提供了一些经验供参考。