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口腔B细胞滤泡性淋巴组织增生(假性淋巴瘤):诊断难题

B-cell Follicular Lymphoid Hyperplasia (Pseudolymphoma) of the Oral Cavity: A Diagnostic Quandary.

作者信息

Selvam Ramya, John Sharon, Sankar Roshna, Khan Eram, Gupta Shalini, Chandra Shaleen

机构信息

Department of Oral and Maxillofacial Pathology and Oral Microbiology, King George's Medical University, Lucknow, India.

Atal Bihari Vajpayee Medical University, Lucknow, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):1029-1032. doi: 10.1007/s12070-023-04086-5. Epub 2023 Jul 27.

Abstract

Pseudolymphoma is a reactive process involving lymphadenopathy, polyclonal proliferation of B or T-cells, simulating oral lymphoma. With its incidence being very rare, only four cases have been reported in oral cavity with the detailed immunocytochemical examination, which can be due to this entity's unawareness, underdiagnosis or overdiagnosis. It is prerogative to perform immunocytochemical investigations to prevent overdiagnosis as lymphoma, which can be debilitating to the patient. Wherein the treatment of pseudolymphoma initially includes topical or intralesional corticosteroid, antibiotics to surgical and radiotherapy based on its etiology. Herein, we discuss B-cell follicular lymphoid hyperplasia previously diagnosed as small round cell tumor.

摘要

假性淋巴瘤是一种反应性过程,涉及淋巴结病、B 细胞或 T 细胞的多克隆增殖,酷似口腔淋巴瘤。其发病率非常罕见,口腔中仅有 4 例经详细免疫细胞化学检查报道,这可能是由于对该实体认识不足、诊断不足或诊断过度所致。进行免疫细胞化学检查以防止过度诊断为淋巴瘤很有必要,因为这可能会使患者衰弱。其中假性淋巴瘤的治疗最初包括局部或病灶内使用皮质类固醇、抗生素,根据病因还可进行手术和放疗。在此,我们讨论了先前被诊断为小圆形细胞瘤的 B 细胞滤泡性淋巴组织增生。

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