Ross John J, Ard Kevin L
Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Open Forum Infect Dis. 2024 Feb 14;11(3):ofae091. doi: 10.1093/ofid/ofae091. eCollection 2024 Mar.
Septic arthritis of the spinal facet joints is increasingly recognized in the era of magnetic resonance imaging, but its epidemiology, clinical features, management, and prognosis are ill-defined.
We review 101 previously published cases and report 16 cases occurring at our institutions between 2006 and 2018.
Most patients presented with fever (60%) and back or neck pain (86%). Radiation into the hip, buttock, or limb was present in 34%. The lumbosacral vertebral segments were involved in 78% of cases. Most cases (64%) were due to . Bacteremia was present in 66% and paraspinal muscle abscesses in 54%. While epidural abscesses were present in 56%, neurologic complications were seen in only 9%, likely because most abscesses arose below the conus medullaris. Neurologic complications were more common with cervical or thoracic involvement than lumbosacral (32% vs 2%, < .0001). Extraspinal infection, such as endocarditis, was identified in only 22% of cases. An overall 98% of patients survived, with only 5% having neurologic sequelae.
Septic arthritis of the facet joint is a distinct clinical syndrome typically involving the lumbar spine and is frequently associated with bacteremia, posterior epidural abscesses, and paraspinal pyomyositis. Neurologic outcomes are usually good with medical management alone.
在磁共振成像时代,脊柱小关节化脓性关节炎越来越受到认可,但其流行病学、临床特征、治疗及预后尚不明确。
我们回顾了101例先前发表的病例,并报告了2006年至2018年间在我们机构发生的16例病例。
大多数患者表现为发热(60%)和背部或颈部疼痛(86%)。34%的患者有向髋部、臀部或肢体的放射痛。78%的病例累及腰骶椎节段。大多数病例(64%)病因是……66%的患者有菌血症,54%的患者有椎旁肌肉脓肿。56%的患者有硬膜外脓肿,而只有9%的患者出现神经并发症,可能是因为大多数脓肿发生在脊髓圆锥以下。神经并发症在颈椎或胸椎受累时比腰骶椎受累更常见(32%对2%,P<0.0001)。仅22%的病例发现有脊柱外感染,如心内膜炎。总体98%的患者存活,只有5%有神经后遗症。
小关节化脓性关节炎是一种独特的临床综合征,通常累及腰椎,且常与菌血症、硬膜外后脓肿及椎旁脓性肌炎相关。仅通过药物治疗,神经功能预后通常良好。