肺癌手术的进展：肺段切除术在早期治疗中的作用。
Advances in lung cancer surgery: the role of segmentectomy in early-stage management.
作者信息
Bertolaccini Luca, Casiraghi Monica, Uslenghi Clarissa, Diotti Cristina, Mazzella Antonio, Caffarena Giovanni, Spaggiari Lorenzo
机构信息
Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
出版信息
Expert Rev Respir Med. 2024 Sep;18(9):669-675. doi: 10.1080/17476348.2024.2324083. Epub 2024 Mar 8.
INTRODUCTION
The evolving landscape of surgical interventions for early-stage non-small cell lung cancer (NSCLC) necessitates a reassessment of the traditional gold standard of lobectomy versus emerging sublobar resections, prompting this critical narrative review.
AREAS COVERED
This review encompasses recent randomized controlled trials, notably JCOG0802/WJOG4607L and CALGB140503, comparing lobectomy and sublobar resections for early-stage NSCLC, focusing on tumor size and recurrence rates. It also discusses the importance of individualized decision-making, future research avenues, and technological advancements in lung cancer surgery.
EXPERT OPINION
In this rapidly evolving field, sublobar resections emerge as a viable alternative to lobectomy for tumors smaller than 2 cm in early-stage NSCLC, necessitating precise patient selection and ongoing technological advancements to optimize outcomes.
引言
早期非小细胞肺癌（NSCLC）手术干预的不断发展态势，使得有必要重新评估肺叶切除术这一传统金标准与新兴的亚肺叶切除术，从而促成了本次重要的叙述性综述。
涵盖领域
本综述纳入了近期的随机对照试验，尤其是JCOG0802/WJOG4607L和CALGB140503，比较了早期NSCLC的肺叶切除术和亚肺叶切除术，重点关注肿瘤大小和复发率。它还讨论了个体化决策的重要性、未来的研究方向以及肺癌手术中的技术进步。
专家观点
在这个快速发展的领域，对于早期NSCLC中小于2厘米的肿瘤，亚肺叶切除术成为肺叶切除术的可行替代方案，这需要精确的患者选择以及持续的技术进步以优化治疗效果。
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