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山羊中由 引起的面部和全身毛霉菌病:山羊真菌感染的病例报告和文献复习。

Facial and systemic mucormycosis caused by in a goat: case report and literature review of fungal infections in goats.

机构信息

Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.

Department of Comparative, Diagnostic and Preventive Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.

出版信息

J Vet Diagn Invest. 2024 May;36(3):463-467. doi: 10.1177/10406387241236751. Epub 2024 Mar 11.

Abstract

An 8-y-old Pygora doe was presented to the University of California-Davis, Veterinary Medical Teaching Hospital because of non-healing facial swelling of 2-wk duration. The lesion grew despite medical treatment, causing discomfort masticating, little-to-no airflow from the right nasal passage, and led to euthanasia. On gross examination, a large facial mass with a draining tract through the skin and hard palate was identified. On section, the mass was brown-pink, homogeneous, and friable. Abscess-like masses were identified in the lungs and kidney. Histopathology of the face, including oral and nasal cavities, salivary glands, and lymph nodes, as well as the lung and kidney lesions, revealed large areas of necrosis with numerous wide ribbon-like, mostly aseptate, fungal hyphae consistent with zygomycetes. PCR for fungal organisms performed on formalin-fixed, paraffin-embedded tissue from the face identified (formerly ) of the order and an sp. The lesion was suspected to have started either as a fungal rhinitis or dental feed impaction, subsequently spreading to the face and systemically to the lungs and kidney. We describe here the lesions associated with facial mucormycosis in a goat and present a literature review of infection in veterinary species and fungal infections in goats.

摘要

一只 8 岁的 Pygora 母羊因面部肿胀 2 周未愈而被送到加利福尼亚大学戴维斯分校兽医教学医院。尽管进行了治疗,但病变仍在生长,导致咀嚼不适、右鼻腔几乎没有气流,并最终被实施安乐死。大体检查发现,皮肤和硬腭有一个大的面部肿块,并有一个排脓道。切开后,肿块呈棕粉色,均匀且易碎。肺部和肾脏中有脓肿样肿块。面部、口腔和鼻腔、唾液腺和淋巴结以及肺部和肾脏病变的组织病理学检查显示,有大面积的坏死,有许多宽的带状、大多无菌的真菌菌丝,符合接合菌。对来自面部的福尔马林固定、石蜡包埋组织进行的真菌 PCR 鉴定出了(以前称为)和属的一个种。怀疑病变最初是真菌性鼻炎或牙齿饲料嵌塞,随后扩散到面部,并系统地扩散到肺部和肾脏。我们在这里描述了与山羊面部毛霉菌病相关的病变,并对兽医种属中的感染和山羊中的真菌感染进行了文献复习。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b933/11110776/2584d6aeca69/10.1177_10406387241236751-fig1.jpg

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