Veterinary Dentistry Specialists, Mt. Laurel, NJ, USA.
Hospital for Veterinary Dentistry and Oral Surgery, Matthews, NC, USA.
J Vet Dent. 2024 Sep;41(5):387-398. doi: 10.1177/08987564231225854. Epub 2024 Mar 22.
Hyperbaric oxygen therapy (HBOT) is utilized as an adjunctive treatment for human and veterinary patients with compromised tissues. Medical records from two veterinary hospitals with HBOT chambers were searched for small animal veterinary dentistry and oral surgery specialty patients. The HBOT records were combined with the medical records from the referring specialty veterinary dentistry and oral surgery services. Clinical indications for HBOT treatments associated with a positive outcome in this case series included resistant bacterial infections, electrical cord injury, bite wound injuries, osteomyelitis, crush/traumatic injuries including mandibular fractures, oral surgery performed at previously irradiated sites, and osteonecrosis, presumably radiation induced. Conditions within this case series that remained unchanged or were associated with partial improvement included preoperative treatment of stomatitis without steroid usage and delayed HBOT treatment for long-term endodontic health of laterally luxated immature permanent mandibular incisors. Eighty-eight percent of the HBOT sessions were tolerated well by the patients in this case series. The most common adverse event was mild anxiety. One patient required oral anxiolytic medications to complete the course of treatment. One patient experienced transient seizure activity and was able to complete that session as well as subsequent sessions at a lower chamber pressure. Future prospective studies are necessary to further evaluate and characterize the potential benefits of HBOT as well as to clarify optimal treatment protocols for specific conditions in veterinary dentistry and oral surgery.
高压氧治疗(HBOT)被用作辅助治疗人类和兽医组织受损的患者。搜索了两家拥有 HBOT 室的兽医医院的医疗记录,以寻找小动物兽医牙科和口腔外科专业的患者。将 HBOT 记录与转诊的兽医牙科和口腔外科服务的医疗记录相结合。在本病例系列中,与治疗结果呈阳性相关的 HBOT 治疗的临床指征包括耐药性细菌感染、电线损伤、咬伤损伤、骨髓炎、挤压/创伤性损伤包括下颌骨骨折、以前接受过放射治疗的部位进行口腔手术,以及可能由辐射引起的骨坏死。在本病例系列中,未发生变化或仅部分改善的情况包括术前无类固醇使用治疗口炎和延迟 HBOT 治疗侧向脱位未成熟恒切牙的长期牙髓健康。在本病例系列中,88%的 HBOT 治疗被患者耐受良好。最常见的不良事件是轻度焦虑。一名患者需要口服镇静药物才能完成整个治疗过程。一名患者出现短暂的癫痫发作,但仍能够完成该治疗过程以及随后在较低压力下进行的治疗过程。未来需要进行前瞻性研究,以进一步评估和描述 HBOT 的潜在益处,并阐明兽医牙科和口腔外科特定疾病的最佳治疗方案。