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西班牙 2030 年的脑膜炎奈瑟菌性脑膜炎:立场文件。

Meningococcal meningitis in Spain in the Horizon 2030: A position paper.

机构信息

Servicio de Microbiología Clínica y Enfermedades Infecciosas del Hospital General Universitario Gregorio Marañón, Universidad Complutense. CIBERES. Ciber de Enfermedades Respiratorias. Madrid, Spain.

出版信息

Rev Esp Quimioter. 2024 Aug;37(4):285-298. doi: 10.37201/req/023.2024. Epub 2024 Mar 22.

Abstract

Meningococcal meningitis (MM) and invasive meningococcal disease remain a major public health problem that generates enormous public alarm. It is caused by Neisseria meningitidis, a Gram-negative diplococcus with an enormous capacity for acute and rapidly progressive disease, both episodic and epidemic in nature, with early diagnosis and treatment playing a major role. It occurs at any age, but is most common in children under 5 years of age followed by adolescents. Although most cases occur in healthy people, the incidence is higher in certain risk groups. Despite advances in reducing the incidence, it is estimated that in 2017 there were around 5 million new cases of MM worldwide, causing approximately 290,000 deaths and a cumulative loss of about 20,000,000 years of healthy life. In Spain, in the 2021/22 season, 108 microbiologically confirmed cases of MM were reported, corresponding to an incidence rate of 0.23 cases per 100,000 inhabitants. This is a curable and, above all, vaccine-preventable disease, for which the World Health Organisation has drawn up a roadmap with the aim of reducing mortality and sequelae by 2030. For all these reasons, the Illustrious Official College of Physicians of Madrid (ICOMEM) and the Medical Associations of 8 other provinces of Spain, have prepared this opinion document on the situation of MM in Spain and the resources and preparation for the fight against it in our country. The COVID-19 and Emerging Pathogens Committee of ICOMEM has invited experts in the field to participate in the elaboration of this document.

摘要

流脑(MM)和侵袭性流脑仍然是一个重大的公共卫生问题,引起了公众的极大恐慌。它是由脑膜炎奈瑟菌引起的,脑膜炎奈瑟菌是一种革兰氏阴性双球菌,具有巨大的急性和快速进展性疾病的能力,具有突发和流行的性质,早期诊断和治疗起着重要作用。它发生在任何年龄,但最常见于 5 岁以下儿童,其次是青少年。尽管大多数病例发生在健康人群中,但某些风险群体的发病率更高。尽管在降低发病率方面取得了进展,但据估计,2017 年全球有大约 500 万例新的 MM 病例,导致约 29 万人死亡,累计损失约 2000 万健康生命年。在西班牙,2021/22 赛季报告了 108 例微生物确诊的 MM 病例,发病率为每 10 万人 0.23 例。这是一种可治愈的疾病,而且,最重要的是,可以通过疫苗预防,世界卫生组织为此制定了路线图,旨在到 2030 年降低死亡率和后遗症。基于所有这些原因,马德里著名的官方医师学院(ICOMEM)和西班牙其他 8 个省份的医疗协会编写了这份关于西班牙 MM 状况以及我们国家对抗该病的资源和准备情况的意见文件。ICOMEM 的 COVID-19 和新兴病原体委员会邀请了该领域的专家参与该文件的编写。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9d7/11231484/31ae8ca21763/revespquimioter-37-285-g001.jpg

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