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探索职业性二氧化硅暴露进展为系统性硬化症的影响:关于二氧化硅诱导的系统性硬化症病例发展的报告。

Exploring the Impact of Occupational Silica Exposure Progressing to Systemic Sclerosis: A Report on the Development of Silica-Induced Systemic Sclerosis Cases.

作者信息

Patro Mahismita, Girija Aswathy, Sarkar Subho, Mohapatra Prasanta R, Shirgaokar Rohit

机构信息

Pulmonary Medicine & Critical Care, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, IND.

出版信息

Cureus. 2024 Feb 21;16(2):e54595. doi: 10.7759/cureus.54595. eCollection 2024 Feb.

Abstract

Erasmus syndrome is an uncommon disease brought on by exposure to silica and later manifests as systemic sclerosis (SSc) with or without silicosis. The body of literature on Erasmus syndrome is scarce. Here, we report two cases of male patients presenting with SSc after silica exposure. One of the patients had worked in the steel industry, and another had worked in the sculpture manufacturing for a decade before the presentation. It is imperative to raise awareness of this uncommon illness because avoiding further exposure remains the mainstay of management. Our case reports reemphasize the importance of occupational history in all patients of SSc.

摘要

伊拉斯谟综合征是一种因接触二氧化硅而引发的罕见疾病,后期可表现为伴有或不伴有矽肺的系统性硬化症(SSc)。关于伊拉斯谟综合征的文献资料匮乏。在此,我们报告两例男性患者在接触二氧化硅后出现SSc的病例。其中一名患者曾在钢铁行业工作,另一名患者在出现症状前曾在雕塑制造业工作了十年。提高对这种罕见疾病的认识至关重要,因为避免进一步接触仍然是治疗的主要手段。我们的病例报告再次强调了职业史在所有SSc患者中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de46/10958239/99fdd111fb9f/cureus-0016-00000054595-i01.jpg

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