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到 2025 年在印度实现结核病消除的进展和挑战:系统评价和荟萃分析。

Progress and challenges in achieving tuberculosis elimination in India by 2025: A systematic review and meta-analysis.

机构信息

Department of Microbiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.

Department of Community and Family Medicine, All India Institute of Medical Sciences, Rajkot, Gujarat, India.

出版信息

PLoS One. 2024 Mar 27;19(3):e0301060. doi: 10.1371/journal.pone.0301060. eCollection 2024.

Abstract

BACKGROUND

Tuberculosis (TB) continues to pose a significant public health challenge in India, which is home to one of the highest TB burdens worldwide. This systematic review and meta-analysis will aim to synthesize the anticipated progress and potential challenges in achieving TB elimination in India by 2025.

METHODS

A comprehensive search will be conducted across multiple databases, including PubMed, Scopus, and Web of Science, to identify relevant studies. The eligibility criteria will encompass individuals diagnosed with TB in India, interventions targeting TB treatment, prevention, or control, and various comparator groups. Outcomes of interest will include incidence reduction, mortality rate, treatment success rate, barriers to TB care, and more. Both quantitative and qualitative data will be synthesized, and the risk of bias will be assessed using established tools.

OUTCOMES

The review is expected to provide a holistic understanding of the TB landscape in India, highlighting the effective interventions and potential challenges in the journey towards TB elimination.

CONCLUSIONS

While it is anticipated that significant progress will be made in the fight against TB in India, challenges are likely to persist. This review will offer a comprehensive roadmap for researchers, policymakers, and healthcare professionals, emphasizing the importance of continued efforts, innovative strategies, and a multi-pronged approach in achieving the goal of TB elimination in India by 2025.

摘要

背景

结核病(TB)仍然是印度面临的重大公共卫生挑战,印度是全球结核病负担最高的国家之一。本系统评价和荟萃分析旨在综合预期的进展和在 2025 年实现印度结核病消除的潜在挑战。

方法

将在多个数据库(包括 PubMed、Scopus 和 Web of Science)中进行全面搜索,以确定相关研究。纳入标准将包括在印度诊断为结核病的个体、针对结核病治疗、预防或控制的干预措施以及各种对照组。感兴趣的结果将包括发病率降低、死亡率、治疗成功率、结核病护理障碍等。将综合使用定量和定性数据,并使用既定工具评估偏倚风险。

结果

该综述预计将全面了解印度的结核病情况,突出显示在实现结核病消除的过程中有效的干预措施和潜在挑战。

结论

尽管预计印度在抗击结核病方面将取得重大进展,但挑战仍将持续存在。本综述将为研究人员、政策制定者和医疗保健专业人员提供全面的路线图,强调在 2025 年实现印度结核病消除目标方面持续努力、创新战略和多管齐下方法的重要性。

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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews.PRISMA 2020 声明:系统评价报告的更新指南。
PLoS Med. 2021 Mar 29;18(3):e1003583. doi: 10.1371/journal.pmed.1003583. eCollection 2021 Mar.

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