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择期卵巢子宫切除术犬的血液血红蛋白值与无创共血氧测定法测量的SpHb之间的相关性

Correlation of Blood Hemoglobin Values with Non-Invasive Co-Oximetry Measurement of SpHb in Dogs Undergoing Elective Ovariohysterectomy.

作者信息

Espinosa-Morales María Fernanda, Miranda-Cortés Agatha Elisa, Mota-Rojas Daniel, Casas-Alvarado Alejandro, Jiménez-Yedra Alejandro, Pérez-Sánchez Alicia Pamela, Hernández-Ávalos Ismael

机构信息

Clinical Pharmacology and Veterinary Anesthesia, Biological Sciences Department, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico (UNAM), Cuautitlán 54714, Mexico.

Neurophysiology of Pain, Behavior and Animal Welfare Assessment, Department of Agricultural and Animal Production (DAAP), Universidad Autónoma Metropolitana (UAM), Xochimilco Campus, Mexico City 04960, Mexico.

出版信息

Animals (Basel). 2024 Mar 7;14(6):822. doi: 10.3390/ani14060822.

Abstract

Cardiovascular function monitoring has been suggested as a key parameter to determine patient stability during the anesthetic process. However, the use of pulse co-oximetry has been suggested as a technology to complement the monitoring of this system as a direct way to assess hemoglobin (Hb) blood concentration. Therefore, this study aimed to correlate and determine the measurement bias between Hb blood levels with continuously determined blood hemoglobin concentration (SpHb) and arterial oxygen content values (SpOC), both obtained by noninvasive co-oximetry in dogs undergoing elective ovariohysterectomy (OVH). A total of 85 clinically healthy bitches of different breeds that were admitted for elective OVH surgery were evaluated. These animals underwent SpHb and SpOC capture after the in vivo setting for the duration of the surgical procedure. Likewise, five minutes before the end of the surgical procedure, a blood sample was obtained directly from the jugular vein to determine the blood concentration of Hb (Hb. The Bland-Altman analysis showed 95% limits of agreement from -4.22 to 4.99 g/dL with a BIAS (mean difference) of 0.384 ± 2.35 g/dL (r = 0.401). SpHb recordings were correlated with oxygen saturation (SpO) (r = 0.995), SpOC (r = 0.992) and with perfusion index (PI) (r = 0.418). Therefore, SpHb presents a moderate positive correlation with direct blood concentration of Hb. This possibly shows that continuous measurement of SpHb by noninvasive co-oximetry is a reliable and advanced alternative for monitoring Hb concentration in dogs under anesthesia.

摘要

心血管功能监测已被视为确定麻醉过程中患者稳定性的关键参数。然而,有人建议使用脉搏血氧饱和度仪作为一种技术来补充该系统的监测,作为评估血红蛋白(Hb)血浓度的直接方法。因此,本研究旨在关联并确定接受择期卵巢子宫切除术(OVH)的犬只通过无创血氧饱和度仪连续测定的血血红蛋白浓度(SpHb)和动脉血氧含量值(SpOC)与Hb血水平之间的测量偏差。总共评估了85只因择期OVH手术入院的不同品种临床健康母犬。这些动物在手术过程的体内设置后进行了SpHb和SpOC采集。同样,在手术结束前五分钟,直接从颈静脉采集血样以测定Hb的血浓度(Hb)。Bland-Altman分析显示一致性界限为-4.22至4.99 g/dL,偏差(平均差异)为0.384±2.35 g/dL(r = 0.401)。SpHb记录与血氧饱和度(SpO)(r = 0.995)、SpOC(r = 0.992)以及灌注指数(PI)(r = 0.418)相关。因此,SpHb与Hb的直接血浓度呈中度正相关。这可能表明通过无创血氧饱和度仪连续测量SpHb是监测麻醉犬Hb浓度的一种可靠且先进的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a4a/10967429/33b227b1367d/animals-14-00822-g001.jpg

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