Department of Orthopedic Surgery, Hanyang University Hospital, Hanyang University College of Medicine, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea.
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro, 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.
Medicina (Kaunas). 2024 Mar 14;60(3):483. doi: 10.3390/medicina60030483.
: Reducing opioid exposure in common pediatric surgeries is of paramount importance. This study aimed to assess the efficacy of regional nerve blocks in reducing opioid exposure while preserving high success rates. : We conducted a retrospective matched cohort study (1:1) including patients with elbow fractures < 12 years old who underwent treatment with percutaneous pinning. Patients were divided into general-anesthesia (GA) and GA-followed-by-supraclavicular-brachial-plexus-block (GA-SCB) groups. The primary outcome was the number of patients administered postoperative rescue opioids. The secondary outcomes included intraoperative and postoperative opioid administration, the time to first request for rescue analgesia, pain scores, block success rate, block performing time, and block-related complications. : In a total of 478 patients, 363 underwent percutaneous pinning, and 86 were cohort-matched (GA: = 43, GA-SCB: = 43). On the first postoperative day, 34 (79.0%) patients in the GA group were administered postoperative rescue opioids, compared with 12 (27.9%) in the GA-SCB group ( < 0.001). All the patients in the GA-SCB group were opioid-free during the intraoperative period. No SCB-associated complications were observed. Total opioid consumption was significantly lower in the GA-SCB group than in the GA group until the first postoperative day (GA vs. GA-SCB, 3.2 ± 3.0 mg vs. 0.9 ± 1.8 mg, < 0.001). : SCB application in pediatric patients who underwent elbow fracture surgery significantly reduced opioid exposure and had a high success rate when performed using ultrasound guidance by an expert. Furthermore, the complication risk and surgical delay were minimal.
: 减少常见儿科手术中的阿片类药物暴露至关重要。本研究旨在评估区域神经阻滞在降低阿片类药物暴露的同时保持高成功率的效果。 : 我们进行了一项回顾性匹配队列研究(1:1),纳入了年龄<12 岁接受经皮穿针治疗的肘部骨折患者。患者分为全身麻醉(GA)和 GA 后锁骨下臂丛阻滞(GA-SCB)组。主要结局是接受术后补救性阿片类药物的患者人数。次要结局包括术中及术后阿片类药物的使用、首次要求解救性镇痛的时间、疼痛评分、阻滞成功率、阻滞操作时间及阻滞相关并发症。 : 在总共 478 名患者中,363 例行经皮穿针治疗,86 名患者进行了队列匹配(GA: = 43,GA-SCB: = 43)。在术后第 1 天,GA 组有 34 名(79.0%)患者接受了术后补救性阿片类药物,而 GA-SCB 组只有 12 名(27.9%)( < 0.001)。GA-SCB 组所有患者在术中均无需使用阿片类药物。未观察到与 SCB 相关的并发症。GA-SCB 组的总阿片类药物消耗量在术后第 1 天明显低于 GA 组(GA 组 vs. GA-SCB 组,3.2 ± 3.0 mg 比 0.9 ± 1.8 mg, < 0.001)。 : 在接受肘部骨折手术的儿科患者中应用 SCB 可显著减少阿片类药物暴露,并且在由专家使用超声引导时成功率较高。此外,并发症风险和手术延迟极小。