Cai Yanni, Pascoletti Giulia, Zioupos Peter, Budair Basil, Zanetti Elisabetta M, Ringrose Trevor J, Junaid Sarah
Cranfield Forensic Institute, Defence Academy of the United Kingdom, Cranfield University, Swindon SN6 8LA, UK.
School of Mechanical, Biomedical and Design Engineering, Aston University, Birmingham B4 7ET, UK.
Life (Basel). 2024 Feb 29;14(3):328. doi: 10.3390/life14030328.
Flatfoot is a condition commonly seen in children; however, there is general disagreement over its incidence, characterization and correction. Painful flatfoot accompanied with musculoskeletal and soft tissue problems requires surgery to avoid arthritis in adulthood, the most common surgical approach being two osteotomies to the calcaneus and medial cuneiform bones of the foot.
This study focuses on the parametrization of these two bones to understand their bone morphology differences in a population sample among 23 normal subjects. Population differences could help in understanding whether bone shape may be an important factor in aiding surgical planning and outcomes.
A total of 45 sets of CT scans of these subjects were used to generate surface meshes of the two bones and converted to be iso-topological meshes, simplifying the application of Generalized Procrustes Analysis and Principal Component Analysis, allowing the main sources of variation between the subjects to be quantified.
For the calcaneus, 16 Principal Components (PCs) and, for the medial cuneiform, 12 PCs were sufficient to describe 90% of the dataset variability. The quantitative and qualitative analyses confirm that for the calcaneus PC1 describes the Achilles attachment location and PC2 largely describes the anterior part of the bone. For the medial cuneiform, PC1 describes the medial part of the bone, while PC2 mainly describes the superior part.
Most importantly, the PCs did not seem to describe the osteotomy sites for both bones, suggesting low population variability at the bone cutting points. Further studies are needed to evaluate how shape variability impacts surgical outcomes. Future implications could include better surgical planning and may pave the way for complex robotic surgeries to become a reality.
扁平足是儿童中常见的病症;然而,对于其发病率、特征及矫正方法,目前尚无定论。伴有肌肉骨骼和软组织问题的疼痛性扁平足需要手术治疗,以避免成年后患关节炎,最常见的手术方法是对跟骨和足内侧楔骨进行两处截骨术。
本研究聚焦于这两块骨头的参数化,以了解23名正常受试者群体样本中它们的骨形态差异。群体差异有助于理解骨形状是否可能是辅助手术规划和手术结果的重要因素。
总共使用了这些受试者的45组CT扫描数据来生成这两块骨头的表面网格,并将其转换为等拓扑网格,简化了广义普罗克拉斯分析和主成分分析的应用,从而能够对受试者之间变异的主要来源进行量化。
对于跟骨,16个主成分(PCs),对于内侧楔骨,12个主成分足以描述90%的数据组变异性。定量和定性分析证实,对于跟骨,主成分1描述跟腱附着位置,主成分2主要描述骨头的前部。对于内侧楔骨,主成分1描述骨头的内侧部分,而主成分2主要描述上部。
最重要的是,主成分似乎并未描述这两块骨头的截骨部位,这表明截骨点处群体变异性较低。需要进一步研究来评估形状变异性如何影响手术结果。未来的意义可能包括更好的手术规划,并可能为复杂的机器人手术成为现实铺平道路。