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住院患者中 OSA 的早期识别和治疗及其对农村人群医疗保健利用的影响:一项真实世界研究。

Early recognition and treatment of OSA in hospitalized patients and its impact on health care utilization in rural population: a real-world study.

机构信息

Division of Pulmonary, Critical Care and Sleep Medicine, West Virginia University School of Medicine, Morgantown, West Virginia.

Harvard Medical School, Boston, Massachusetts.

出版信息

J Clin Sleep Med. 2024 Aug 1;20(8):1313-1319. doi: 10.5664/jcsm.11146.

Abstract

STUDY OBJECTIVES

Obstructive sleep apnea (OSA) is a highly prevalent, yet underdiagnosed, condition. Due to its adverse impact on risk for cardiopulmonary disorders, there is interest in proactive screening of OSA in hospitalized patients. We studied the long-term outcome of such screened patients who were initiated on positive airway pressure therapy.

METHODS

Hospitalized patients who screened positive for OSA and were confirmed with postdischarge polysomnography were dichotomized by positive airway pressure therapy adherence and followed for a period of 12 months to evaluate for the composite end point of hospital readmissions and emergency department visits for cardiopulmonary reasons. Cost analysis between the 2 groups was also conducted.

RESULTS

A total of 2,042 hospitalized patients were assessed for OSA as part of a hospital sleep medicine program from August 2019-June 2023. Of these, 293 patients were diagnosed with OSA and prescribed positive airway pressure therapy. Of these 293 patients, 108 were adherent to therapy and 185 were nonadherent. The overall characteristics of the groups included a mean (standard deviation) age of 58 years (12.82), mean body mass index (kg/m) of 39.72 (10.71), 57% male sex, and apnea-hypopnea index of 25.49 (26). Of the patients, 78%, 41%, and 43% had hypertension, congestive heart failure, and diabetes mellitus, respectively. The composite end point of hospital readmissions and emergency department visits for cardiovascular and pulmonary reasons was significantly higher in the nonadherent group than in the adherent group (hazard ratio, 1.24; 95% confidence interval, 1-1.54) ( = .03). The cost of care for both hospital billing as well as professional billing was higher for the nonadherent group ($1,455.60 vs $1,723.50, = .004 in hospital billing cost and $130.90 vs $144.70, < .001 in professional billing). Length of stay was higher for nonadherent patients (2.7 ± 5.1 days vs 2.3 ± 5.9 days).

CONCLUSIONS

Hospitalized patients diagnosed with OSA and adherent to therapy have reduced readmissions and emergency department visits for cardiopulmonary reasons 12 months after discharge. Adherent patients have reduced cost of health care and length of stay during hospitalizations.

CITATION

Sharma S, Stansbury R, Srinivasan P, et al. Early recognition and treatment of OSA in hospitalized patients and its impact on health care utilization in rural population: a real-world study. . 2024;20(8):1313-1319.

摘要

研究目的

阻塞性睡眠呼吸暂停(OSA)是一种高发但诊断不足的疾病。由于其对心肺疾病风险的不利影响,人们对住院患者进行 OSA 的主动筛查产生了兴趣。我们研究了接受正压通气治疗的经筛查患者的长期结果。

方法

筛查出 OSA 阳性并经出院后多导睡眠图(PSG)检查确诊的住院患者,根据正压通气治疗依从性分为两组,并随访 12 个月,以评估因心肺原因再次住院和急诊就诊的复合终点。还对两组之间的成本分析进行了比较。

结果

2019 年 8 月至 2023 年 6 月,共有 2042 名住院患者作为医院睡眠医学计划的一部分接受了 OSA 评估。其中,293 名患者被诊断为 OSA 并开具了正压通气治疗处方。这 293 名患者中,108 名患者依从治疗,185 名患者不依从治疗。两组患者的总体特征包括平均(标准差)年龄 58 岁(12.82)、平均体重指数(kg/m)39.72(10.71)、57%为男性、呼吸暂停低通气指数 25.49(26)。其中,78%、41%和 43%的患者分别患有高血压、充血性心力衰竭和糖尿病。在心血管和肺部原因方面,再次住院和急诊就诊的复合终点在不依从组明显高于依从组(危险比,1.24;95%置信区间,1-1.54)( =.03)。不依从组的住院和专业计费的医疗费用均较高(医院计费成本分别为 1455.60 美元和 1723.50 美元, =.004,专业计费成本分别为 130.90 美元和 144.70 美元, <.001)。不依从患者的住院时间更长(2.7±5.1 天 vs 2.3±5.9 天)。

结论

在出院后 12 个月,诊断为 OSA 并接受治疗的住院患者因心肺原因再次住院和急诊就诊的次数减少。依从治疗的患者减少了医疗保健费用,并缩短了住院时间。

引文

Sharma S, Stansbury R, Srinivasan P, et al. 早期识别和治疗住院患者的 OSA 及其对农村人群医疗保健利用的影响:一项真实世界研究。 2024;20(8):1313-1319.

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