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新冠病毒疾病(COVID-19)死亡率悖论(美国与非洲):大规模疫苗接种与早期治疗

COVID-19 mortality paradox (United States Africa): Mass vaccination early treatment.

作者信息

Kelleni Mina Thabet

机构信息

Department of Pharmacology, College of Medicine, Minia University, Minya 61111, Egypt.

出版信息

World J Exp Med. 2024 Mar 20;14(1):88674. doi: 10.5493/wjem.v14.i1.88674.

Abstract

The coronavirus disease 2019 (COVID-19) mortality rate in 55 African countries is almost 4.5 times lower than in the coronavirus disease 2019 (COVID-19) despite Africa having over 4.2 times more people. This mortality paradox is also evident when comparing Nigeria, a heavily populated, poorly vaccinated and weakly mandated country to Israel, a small, highly vaccinated and strictly mandated country. Nigeria has almost 4 times lower COVID mortality than Israel. In this Field of Vision perspective, I explain how this paradox has evolved drawing upon my academic, clinical and social experience. Since April 2020, I've developed and been using the Egyptian immune-modulatory Kelleni's protocol to manage COVID-19 patients including pediatric, geriatric, pregnant, immune-compromised and other individuals suffering from multiple comorbidities. It's unfortunate that severe acute respiratory syndrome coronavirus 2 is still evolving accompanied by more deaths. However in Africa, we've been able to live without anxiety or mandates throughout the pandemic because we trust science and adopted early treatment using safe, and effective repurposed drugs that have saved the majority of COVID-19 patients. This article represents an African and Egyptian tale of honor.

摘要

2019冠状病毒病(COVID-19)在55个非洲国家的死亡率几乎比在其他地区低4.5倍,尽管非洲人口比其他地区多4.2倍以上。将人口众多、疫苗接种率低且管控宽松的尼日利亚与面积小、疫苗接种率高且管控严格的以色列相比,这种死亡率悖论也很明显。尼日利亚的COVID死亡率几乎比以色列低4倍。在这篇“视野”文章中,我凭借自己的学术、临床和社会经验,解释了这种悖论是如何演变的。自2020年4月以来,我制定并一直在使用埃及免疫调节药物凯莱尼方案来治疗COVID-19患者,包括儿童、老年人、孕妇、免疫功能低下者以及患有多种合并症的其他患者。不幸的是,严重急性呼吸综合征冠状病毒2仍在演变,死亡人数也在增加。然而在非洲,在整个疫情期间我们能够无忧无虑地生活,无需强制要求,因为我们相信科学,并采用安全有效的已获批准药物进行早期治疗,这些药物挽救了大多数COVID-19患者的生命。本文讲述了一个非洲和埃及的荣耀故事。

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