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DFDBA与含DFDBA的PRF治疗II度根分叉病变的对比评估——一项临床试验

Comparative Evaluation of DFDBA versus PRF with DFDBA in Treatment of Grade-II Furcation Defects - A Clinical Trial.

作者信息

Desai Kinjal N, Thakkar Rohit R, Patel Jalpa, Gupta Ekta, Trivedi Namrata, Sampat Dipali

机构信息

Department of Periodontology and Implantology, Siddhpur Dental College and Hospital, Siddhpur, Gujarat, India.

Department of Periodontology and Implantology, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.

出版信息

J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S794-S796. doi: 10.4103/jpbs.jpbs_1016_23. Epub 2024 Feb 29.

Abstract

BACKGROUND

In order to determine whether a method is more successful for treating a grade-II furcation deficiency, this randomized trial will compare demineralized freeze-dried bone allograft (DFDBA) to platelet-rich fibrin with DFDBA.

MATERIALS AND METHODS

Twenty systematically healthy patients between the ages of 30 and 60 with a grade-II furcation were evaluated pre and postoperatively for changes in the modified plaque index, probing depth, relative vertical and horizontal clinical attachment level, gingival marginal level, and radiographic bone defect.

RESULTS

The test group significantly outperformed the control group on all clinical and radiological measures.

CONCLUSION

The experimental group improved at both clinical attachment levels and had a higher decrease in probing depth than the control group did.

摘要

背景

为了确定一种方法在治疗Ⅱ度根分叉病变方面是否更成功,本随机试验将脱矿冻干骨同种异体移植(DFDBA)与富含血小板纤维蛋白联合DFDBA进行比较。

材料与方法

对20例年龄在30至60岁之间、患有Ⅱ度根分叉病变的系统健康患者在术前和术后评估改良菌斑指数、探诊深度、相对垂直和水平临床附着水平、牙龈边缘水平以及影像学骨缺损的变化。

结果

在所有临床和放射学指标上,试验组均显著优于对照组。

结论

与对照组相比,试验组在临床附着水平上均有改善,且探诊深度下降幅度更大。

相似文献

1
Comparative Evaluation of DFDBA versus PRF with DFDBA in Treatment of Grade-II Furcation Defects - A Clinical Trial.
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S794-S796. doi: 10.4103/jpbs.jpbs_1016_23. Epub 2024 Feb 29.

本文引用的文献

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Immune Response: The Key to Bone Resorption in Periodontal Disease.
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Effect of Autologous Platelet Rich Fibrin in Human Mandibular Molar Grade II Furcation Defects- A Randomized Clinical Trial.
J Clin Diagn Res. 2017 Apr;11(4):ZC73-ZC77. doi: 10.7860/JCDR/2017/23277.9694. Epub 2017 Apr 1.
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Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial.
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A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro.
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Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF).
Trends Biotechnol. 2009 Mar;27(3):158-67. doi: 10.1016/j.tibtech.2008.11.009. Epub 2009 Jan 31.

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