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甲状旁腺激素相关肽高钙血症作为子宫内膜透明细胞癌的一种表现

Parathyroid Hormone Related Peptide Hypercalcemia as a Presentation of Endometrial Clear Cell Carcinoma.

作者信息

Georges Claudia, Adhikari Biplov, Koundaveety Soumya, Jones Robert, Paudel Kalyan, Haas Christopher

机构信息

Department of Medicine, MedStar Health Internal Medicine Residency Program, MedStar Union Memorial Hospital, Baltimore, MD, USA.

Department of Pathology, MedStar Franklin Square Medical Center, Baltimore, MD, USA.

出版信息

J Community Hosp Intern Med Perspect. 2023 Nov 4;13(6):67-70. doi: 10.55729/2000-9666.1271. eCollection 2023.

Abstract

Hypercalcemia is a frequent complication of solid tumors and hematologic malignancies yet is only rarely associated with endometrial clear cell carcinoma. Here we report on a 70-year-old female who presented in the context of hip fracture and was incidentally found to have humoral hypercalcemia of malignancy secondary to endometrial clear cell carcinoma. This rare association makes endometrial cancer one of the differential diagnoses to be considered when assessing incidentally found symptomatic or asymptomatic hypercalcemia in the appropriate patient population.

摘要

高钙血症是实体瘤和血液系统恶性肿瘤常见的并发症,但与子宫内膜透明细胞癌的关联却极为罕见。在此,我们报告一例70岁女性患者,该患者因髋部骨折就诊,偶然发现患有继发于子宫内膜透明细胞癌的恶性肿瘤性体液性高钙血症。这种罕见的关联使得子宫内膜癌成为在合适的患者群体中评估偶然发现的有症状或无症状高钙血症时需要考虑的鉴别诊断之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a091/11000832/87fd77514e91/jchim-13-06-067f1.jpg

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