School of Computer Science and Technology, Anhui University, Hefei 230601, China; Anhui Province Key Laboratory of Multimodal Cognitive Computation, Anhui University, Hefei 230601, China.
National Centre for International Research in Cell and Gene Therapy, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.
J Neurosci Methods. 2024 Jun;406:110132. doi: 10.1016/j.jneumeth.2024.110132. Epub 2024 Apr 9.
Traditional therapist-based rehabilitation training for patients with movement impairment is laborious and expensive. In order to reduce the cost and improve the treatment effect of rehabilitation, many methods based on human-computer interaction (HCI) technology have been proposed, such as robot-assisted therapy and functional electrical stimulation (FES). However, due to the lack of active participation of brain, these methods have limited effects on the promotion of damaged nerve remodeling.
Based on the neurofeedback training provided by the combination of brain-computer interface (BCI) and exoskeleton, this paper proposes a multimodal brain-controlled active rehabilitation system to help improve limb function. The joint control mode of steady-state visual evoked potential (SSVEP) and motor imagery (MI) is adopted to achieve self-paced control and thus maximize the degree of brain involvement, and a requirement selection function based on SSVEP design is added to facilitate communication with aphasia patients.
In addition, the Transformer is introduced as the MI decoder in the asynchronous online BCI to improve the global perception of electroencephalogram (EEG) signals and maintain the sensitivity and efficiency of the system.
In two multi-task online experiments for left hand, right hand, foot and idle states, subject achieves 91.25% and 92.50% best accuracy, respectively.
Compared with previous studies, this paper aims to establish a high-performance and low-latency brain-controlled rehabilitation system, and provide an independent and autonomous control mode of the brain, so as to improve the effect of neural remodeling. The performance of the proposed method is evaluated through offline and online experiments.
传统的以治疗师为基础的运动障碍患者康复训练既费力又昂贵。为了降低康复成本,提高治疗效果,许多基于人机交互(HCI)技术的方法被提出,如机器人辅助治疗和功能性电刺激(FES)。然而,由于大脑缺乏主动参与,这些方法对促进受损神经重塑的效果有限。
本文基于脑机接口(BCI)和外骨骼相结合提供的神经反馈训练,提出了一种多模态脑控主动康复系统,以帮助改善肢体功能。采用稳态视觉诱发电位(SSVEP)和运动想象(MI)的联合控制模式,实现自主控制,从而最大限度地提高大脑的参与程度,并添加基于 SSVEP 设计的需求选择功能,以方便与失语症患者进行交流。
此外,将 Transformer 引入异步在线 BCI 中作为 MI 解码器,以提高脑电图(EEG)信号的全局感知能力,并保持系统的敏感性和效率。
在针对左手、右手、脚和空闲状态的两个多任务在线实验中,受试者分别达到了 91.25%和 92.50%的最佳准确率。
与以往的研究相比,本文旨在建立一个高性能、低延迟的脑控康复系统,并提供一种独立和自主的大脑控制模式,以提高神经重塑的效果。通过离线和在线实验对所提出方法的性能进行了评估。