Tejada Meza H, Lambea Gil Á, Villar Yus C, Pérez Lázaro C, Navarro Pérez M P, Campello Morer I, Giménez Muñoz Á, Artal Roy J, Alberti González O, Hernando Quintana N, Ruiz Palomino P, Crespo Burillo J A, García Arguedas C, Ballester Marco L, Palacin Larroy M, Seral Moral M, Marta Moreno J
Sección de Neurovascular, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, España.
Unidad de Neurointervencionismo, Servicio de Radiología, Hospital Universitario Miguel Servet, Zaragoza, España.
Neurologia. 2021 Sep;36(7):531-536. doi: 10.1016/j.nrl.2021.02.008. Epub 2021 Feb 23.
The COVID-19 pandemic has had an impact on ischaemic stroke management, with a reported decrease in hospital admissions, and even disruptions in healthcare and increased in-hospital mortality. However, there is a lack of evidence on the impact of the pandemic on functional prognosis. The aim of this study is to analyse the effect of the COVID-19 pandemic on the 3-month functional outcomes of patients hospitalised due to acute ischaemic stroke in Aragon (Spain).
We reviewed the data of all patients admitted due to ischaemic stroke to any hospital in our regional healthcare system between 30 December 2019 and 3 May 2020. We compared modified Rankin Scale scores and mortality at 3 months in patients hospitalised before and after the declaration of a state of emergency due to the COVID-19 pandemic.
In total, 318 patients with acute ischaemic stroke met our inclusion criteria. No differences were observed between periods in global or specific characteristics, with the exception of a higher proportion of patients older than 80 years during the first period (42.2% vs. 29.0%, =.028). In the comparative analysis, we found no significant differences in mortality (12.3 vs. 7.9, =.465) or in the proportion of patients with modified Rankin Scale scores ≤ 2 (57.7% vs. 57.1%, =.425) at 3 months.
To our knowledge, this is the first study to analyse the impact of COVID-19 pandemic on the 3-month functional outcomes of patients with ischaemic stroke. In our region, there has been no increase in rates of mortality or disability at 3 months in patients admitted due to ischaemic stroke during the pandemic.
新冠疫情对缺血性卒中的治疗产生了影响,据报道,医院收治人数有所下降,甚至医疗保健出现中断,住院死亡率上升。然而,关于疫情对功能预后影响的证据不足。本研究的目的是分析新冠疫情对西班牙阿拉贡地区因急性缺血性卒中住院患者3个月功能结局的影响。
我们回顾了2019年12月30日至2020年5月3日期间在我们地区医疗系统内任何医院因缺血性卒中入院的所有患者的数据。我们比较了因新冠疫情宣布进入紧急状态之前和之后住院患者3个月时的改良Rankin量表评分和死亡率。
共有318例急性缺血性卒中患者符合我们的纳入标准。除第一阶段80岁以上患者比例较高外(42.2%对29.0%,P = 0.028),各时期在总体或特定特征方面未观察到差异。在比较分析中,我们发现3个月时死亡率(12.3对7.9,P = 0.465)或改良Rankin量表评分≤2的患者比例(57.7%对57.1%,P = 0.425)无显著差异。
据我们所知,这是第一项分析新冠疫情对缺血性卒中患者3个月功能结局影响的研究。在我们地区,疫情期间因缺血性卒中入院患者3个月时的死亡率或残疾率没有增加。