Three recent breakthroughs in CAR T cells for the treatment of glioblastoma: Is it the light at the end of the tunnel?
作者信息
Lowenstein Pedro R, Varela Maria Luisa, Castro Maria G
机构信息
Department of Neurosurgery, The University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI 48109, USA.
Department of Neurosurgery, The University of Michigan, Ann Arbor, MI 48109, USA.
出版信息
Mol Ther. 2024 May 1;32(5):1187-1189. doi: 10.1016/j.ymthe.2024.04.018. Epub 2024 Apr 17.
Abstract
摘要
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1
Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results.
Nat Med. 2024 May;30(5):1320-1329. doi: 10.1038/s41591-024-02893-z. Epub 2024 Mar 13.
2
Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma.
N Engl J Med. 2024 Apr 11;390(14):1290-1298. doi: 10.1056/NEJMoa2314390. Epub 2024 Mar 13.
3
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Nat Med. 2024 Apr;30(4):1001-1012. doi: 10.1038/s41591-024-02875-1. Epub 2024 Mar 7.
4
Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial.
Clin Cancer Res. 2022 Jun 13;28(12):2527-2535. doi: 10.1158/1078-0432.CCR-21-4283.
5
Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma.
Neuro Oncol. 2022 Aug 1;24(8):1318-1330. doi: 10.1093/neuonc/noac024.
6
Emerging Cellular Therapies for Cancer.
Annu Rev Immunol. 2019 Apr 26;37:145-171. doi: 10.1146/annurev-immunol-042718-041407. Epub 2018 Dec 10.
7
Targeting tumours with genetically enhanced T lymphocytes.
Nat Rev Cancer. 2003 Jan;3(1):35-45. doi: 10.1038/nrc971.
8
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.
Science. 1996 Apr 12;272(5259):263-7. doi: 10.1126/science.272.5259.263.
9
Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.
Proc Natl Acad Sci U S A. 1989 Dec;86(24):10024-8. doi: 10.1073/pnas.86.24.10024.
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