Akdoğan Özlem, Yapar Derya, Uysal-Tan Funda, Tunçel-Öztürk Pınar, Kaplan Gülcan, Kocagül-Çelikbaş Aysel, Baykam Nurcan
Department of Infectious Diseases and Clinical Microbiology, Hitit University School of Medicine, Çorum, Turkey.
Department of Neurology, Hitit University School of Medicine, Çorum, Turkey.
Infect Dis Clin Microbiol. 2022 Dec 21;4(4):285-288. doi: 10.36519/idcm.2022.155. eCollection 2022 Dec.
Leptospirosis can present with severe cases such as polymyositis, peripheral neuropathy, and rarely, Guillain-Barré Syndrome (GBS). This paper reports a case who presented with dysarthria and GBS. A female patient presented with complaints of weakness, dizziness, diarrhea, and dysarthric. Her assessments included muscle strength globally 4/5 and deep tendon reflexes as hypoactive. An electromyographic examination was performed with the increase of weakness in the lower extremities, which indicated findings compatible with GBS. Antibodies against serovar Patoc 1 at 1/400 titer were detected in the microscopic agglutination test (MAT). Neurological involvement in leptospirosis cases can range from meningoencephalitis to GBS.
钩端螺旋体病可表现为严重病例,如多发性肌炎、周围神经病,罕见的还有吉兰-巴雷综合征(GBS)。本文报告1例以构音障碍和GBS为表现的病例。1例女性患者主诉有乏力、头晕、腹泻及构音障碍。其评估结果包括全身肌力为4/5级,深部腱反射减弱。随着下肢无力加重进行了肌电图检查,结果提示符合GBS。在显微镜凝集试验(MAT)中检测到抗帕托克1型血清型抗体,滴度为1/400。钩端螺旋体病病例的神经受累范围可从脑膜脑炎到GBS。