Independent Consultant, Brookfield, Wisconsin, USA.
Med Phys. 2024 Jul;51(7):4607-4621. doi: 10.1002/mp.17075. Epub 2024 Apr 23.
Motion induced image artifacts have been the focus of many investigations for x-ray computed tomography (CT). Methodologies of combating patient motion include the use of gating devices to optimize the data acquisition, reduction in patient scan time via faster gantry rotation and large detector coverage, and the development of advanced reconstruction and post-processing algorithms to minimize motion artifacts.
Previously proposed approaches are generally "global" in nature in that motion is characterized for the entire image. It is well known, however, that the presence of motion artifact in a CT image is highly nonuniform. When there is a lack of automated and quantitative local measure indicating the presence and the severity of motion artifacts in a local region, the quality of the reconstructed images depends heavily on the CT operator's rigor and experience. Even when an operator is informed of the presence of motion, little information is provided about the nature of the motion artifact to understand its relevance to the clinical task at hand. In this paper, we propose an image-space spatial- and temporal-consistency metric (CM) to detect and characterize the local motion.
In a non-rigid human organ, such as the lung, there are many small and rigid objects (target objects), such as blood vessels and nodules, distributed throughout the organ. If motion can be characterized for these target objects, we obtain a complete motion map for the organ. To accomplish this, a preliminary image reconstruction is carried out to identify the target objects and establish region-of-interests for consistency-metric calculation. The CM is then obtained based on the backprojected intensity difference between the object region and its circular background. For a stationary object, the accumulation of this quantity over views is linear. When a target object moves, nonlinear behavior exhibits and a quantitative measure of linearity indicates the severity of motion.
Extensive computer simulation was utilized to confirm the validity of the theory. These tests stress the sensitivity of the proposed CM to the target object size, object shape, in-plane motion, cross-plane motion, cone-beam effect, and complex background. Results confirm that the proposed approach is robust under different testing conditions. The proposed CM is further validated using a cardiac scan of a swine, and the proposed CM correlates well with the visual inspection of the artifact in the reconstructed images.
In this paper, we have demonstrated the efficacy of the proposed CM for motion detection. Unlike previously proposed approaches where the consistency condition is derived for the entire image or the entire imaging volume, the proposed metric is well localized so that different zones in a patient anatomy can be individually characterized. In addition, the proposed CM provides a quantitative measure on a view-by-view basis so that the severity of motion is consistently estimated over time. Such information can be used to optimize the image reconstruction process and minimize the motion artifact.
运动引起的图像伪影一直是 X 射线计算机断层扫描(CT)的研究焦点。对抗患者运动的方法包括使用门控设备来优化数据采集,通过更快的旋转架旋转和更大的探测器覆盖范围来减少患者扫描时间,以及开发先进的重建和后处理算法来最小化运动伪影。
以前提出的方法通常在本质上是“全局”的,因为运动是针对整个图像进行描述的。然而,众所周知,CT 图像中的运动伪影高度不均匀。当缺乏自动和定量的局部指标来指示局部区域的运动伪影的存在和严重程度时,重建图像的质量严重依赖于 CT 操作人员的严谨性和经验。即使操作人员被告知存在运动,也几乎没有提供有关运动伪影性质的信息,以了解其与当前临床任务的相关性。在本文中,我们提出了一种基于图像空间的时空一致性度量(CM)来检测和描述局部运动。
在非刚性人体器官(如肺)中,有许多分布在整个器官中的小而刚性的物体(目标物体),如血管和结节。如果可以对这些目标物体进行描述,我们就可以获得器官的完整运动图。为了实现这一点,首先进行初步的图像重建以识别目标物体并为一致性度量计算建立感兴趣区域。然后基于目标区域与其圆形背景之间的反向投影强度差来获得 CM。对于静止的物体,该量在视图上的累积是线性的。当目标物体移动时,会表现出非线性行为,并且线性度的定量度量表示运动的严重程度。
我们利用广泛的计算机模拟来验证理论的有效性。这些测试强调了所提出的 CM 对目标物体大小、物体形状、平面内运动、平面外运动、锥束效应和复杂背景的敏感性。结果证实,该方法在不同测试条件下具有稳健性。我们还使用猪的心脏扫描进一步验证了所提出的 CM,并且所提出的 CM 与重建图像中伪影的视觉检查很好地相关。
在本文中,我们证明了所提出的 CM 用于运动检测的有效性。与以前提出的方法不同,这些方法是从整个图像或整个成像体积推导一致性条件,所提出的度量是很好的局部化的,因此可以单独描述患者解剖结构的不同区域。此外,所提出的 CM 提供了基于视图的定量度量,因此可以随着时间的推移一致地估计运动的严重程度。这些信息可用于优化图像重建过程并最小化运动伪影。