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吞噬作用与肿瘤关系的研究进展

Progress of research on the relationship between efferocytosis and tumor.

作者信息

Yao Xuexin, Zhang Ling, Sun Siyi, Fu Aishuang, Ge Yanlei

机构信息

North China University of Science and Technology Affiliated Hospital, Tangshan, China.

出版信息

Front Oncol. 2024 Apr 9;14:1361327. doi: 10.3389/fonc.2024.1361327. eCollection 2024.

Abstract

Tumors are genetic changes that develop in an organism as a result of many internal and external causes. They affect the biological behavior of cells, cause them to grow independently, and give rise to new, perpetually proliferating organisms. Recent research has supported the critical function of tumor-associated macrophages in the development, progression, and metastasis of tumors through efferocytosis. Yet, there is still much to learn about the mechanisms behind their contribution to tumor pathological processes. As a result, it's critical to actively investigate how cytosolic processes contribute to the growth of tumors and to create novel therapeutic approaches.

摘要

肿瘤是由于多种内部和外部原因在生物体中发生的基因变化。它们影响细胞的生物学行为,使其独立生长,并产生新的、不断增殖的生物体。最近的研究支持了肿瘤相关巨噬细胞通过胞葬作用在肿瘤发生、发展和转移中的关键作用。然而,关于它们对肿瘤病理过程贡献背后的机制仍有许多需要了解的地方。因此,积极研究胞质过程如何促进肿瘤生长并开发新的治疗方法至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32bf/11035832/a61fc4c1cfdd/fonc-14-1361327-g001.jpg

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