Chang Ya-Hui, Lin Chung-Ying, Chou Yu-Tsung, Chen Hung-Yu, Su Hui-Chen, Wu Yi-Lin, Yang Yi-Ching, Hou Wen-Hsuan
Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
BMC Geriatr. 2024 Apr 25;24(1):370. doi: 10.1186/s12877-024-04969-4.
Intrinsic capacity (IC) is a comprehensive indicator of the overall well-being of older adults, and assessing of IC can help identify early stage of disability and tailor intervention to individual needs. However, there is a lack of effective and simple IC assessment tools. This study aimed to establish predictive scoring algorithms of IC to identify older adults at high risk of impaired functional ability.
We conducted a cross-sectional study in Southern Taiwan, measuring IC using 7 subitems: cognition, locomotion, vitality, vision, hearing, psychological well-being, and medication usage were measured. Functional ability outcomes included frailty, basic activities of daily living, and instrumental activities of daily living (IADL). The capability of 7 domains of IC in predicting functional ability was assessed by multivariable logistic regression. The prediction of capability of scoring algorithms was indicated by receiver operating characteristic (AUC) curves and measures of sensitivity and specificity.
A total of 1,152 older adults were recruited and analyzed. Locomotion emerged as a significant predictor of IADL disability and worsening frailty. The IC-based weighted scoring algorism for predicting IADL demonstrated satisfactory capability (AUC: 0.80), as did the algorithm for predicting worsening frailty (AUC: 0.90). The optimal cutoff points for predicting IADL disability and frailty worse were estimated respectively at 13 and 16, with sensitivity/specificity values of 0.74/0.75 for the IADL prediction algorithm and 0.92/0.77 for the frailty prediction algorithm.
Our 7-domain IC screening tool proves to be sensitive and practical for early identification of functional disability and frailty among community-dwelling older adults in Taiwan.
内在能力(IC)是老年人整体健康状况的综合指标,评估IC有助于识别残疾早期阶段并根据个体需求制定干预措施。然而,目前缺乏有效且简单的IC评估工具。本研究旨在建立IC的预测评分算法,以识别功能能力受损风险较高的老年人。
我们在台湾南部进行了一项横断面研究,使用7个分项测量IC:认知、运动能力、活力、视力、听力、心理健康和药物使用情况。功能能力结果包括衰弱、基本日常生活活动和工具性日常生活活动(IADL)。通过多变量逻辑回归评估IC的7个领域预测功能能力的能力。预测评分算法的能力通过受试者工作特征(AUC)曲线以及敏感性和特异性指标来表示。
共招募并分析了1152名老年人。运动能力是IADL残疾和衰弱加重的重要预测因素。基于IC的预测IADL的加权评分算法显示出令人满意的能力(AUC:0.80),预测衰弱加重的算法也是如此(AUC:0.90)。预测IADL残疾和衰弱加重的最佳截断点分别估计为13和16,IADL预测算法的敏感性/特异性值为0.74/0.75,衰弱预测算法的敏感性/特异性值为0.92/0.77。
我们的7领域IC筛查工具被证明对于台湾社区居住老年人中功能残疾和衰弱的早期识别具有敏感性和实用性。