CHU Besançon, Pôle Pharmacie, 25030, Besançon, France.
Qualees, Paris, France.
Support Care Cancer. 2024 Apr 30;32(5):318. doi: 10.1007/s00520-024-08517-z.
To ensure the safe use of oral anticancer drugs, oncology pharmacy consultations (OPCs) have been established in France. They are conditioned by the needs, expectations, and involvement of the patients in their care. Thus, it is essential to elicit their preferences. The discrete-choice experiment (DCE) is a method recommended by the ISPOR for such a task. The "selection and validation of attributes and their values" step is fundamental in this process. In this context, the aim of this study was to present our research approach to identify and validate the attributes that characterize an OPC and their values.
Due to the lack of relevant published data in the literature, the focus-group method was used in accordance with good research practices for the application of conjoint-analysis of the ISPOR. The two-round Delphi method was used to validate the attributes and their values identified by the focus-group method.
The focus-group method enabled identification of nine attributes. Thirty-seven healthcare professionals at a national level, including 30 pharmacists and seven physicians, were selected to take part in the Delphi procedure. Seven attributes (frequency, planification, operation mode, duration, content, written support, and report) and their values were thus validated.
Based on these results, the next step will be to elicit patient preferences for OPCs and to then shed light on the issues of pharmaceutical support for patients by comparing their preferences with those of informal caregivers and, in particular, those of the healthcare professionals involved in their care.
为确保口服抗癌药物的安全使用,法国已设立肿瘤药学咨询(OPC)。这些咨询取决于患者对护理的需求、期望和参与程度。因此,了解患者的偏好至关重要。离散选择实验(DCE)是 ISPOR 推荐用于此类任务的方法。在此过程中,“选择和验证属性及其值”步骤是基础。在此背景下,本研究旨在介绍我们的研究方法,以确定和验证描述 OPC 的属性及其值。
由于文献中缺乏相关的已发表数据,根据 ISPOR 联合分析的良好研究实践,使用焦点小组方法。采用两轮 Delphi 法对焦点小组方法确定的属性及其值进行验证。
焦点小组方法确定了九个属性。在全国范围内选择了 37 名医疗保健专业人员,包括 30 名药剂师和 7 名医生,参加 Delphi 程序。因此,验证了七个属性(频率、计划、运作模式、持续时间、内容、书面支持和报告)及其值。
基于这些结果,下一步将是通过比较患者、非专业照护者(尤其是参与患者护理的医疗保健专业人员)的偏好,来了解患者对 OPC 的偏好,并阐明患者药物支持方面的问题。