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通过凝胶化动力学改变低分子量凝胶性质的方法。

Methods of changing low molecular weight gel properties through gelation kinetics.

作者信息

Ginesi Rebecca E, Draper Emily R

机构信息

School of Chemistry, University of Glasgow, Glasgow, UK, G12 8QQ, UK.

出版信息

Soft Matter. 2024 May 15;20(19):3887-3896. doi: 10.1039/d4sm00238e.

Abstract

Low molecular weight gels continue to attract notable interest, with many potential applications. However, there are still significant gaps in our understanding of these systems and the correlation between the pre-gel and final gel states. The kinetics of the gelation process plays a crucial role in the bulk properties of the hydrogel and presents an opportunity to fine-tune these systems to meet the requirements of the chosen application. Therefore, it is possible to use a single gelator for multiple applications. This review discusses four ways to modify the pre-gelled structures before triggering gelation. Such modifications can enhance the material's intended performance, which may result in significant advancements in high-tech areas, such as drug delivery, cell culturing, electronics, and tissue engineering.

摘要

低分子量凝胶因其众多潜在应用而持续吸引着显著关注。然而,我们对这些体系以及凝胶前状态与最终凝胶状态之间的关联的理解仍存在重大差距。凝胶化过程的动力学在水凝胶的整体性质中起着关键作用,并提供了一个微调这些体系以满足所选应用需求的机会。因此,有可能使用单一的凝胶剂实现多种应用。本综述讨论了在引发凝胶化之前修饰预凝胶结构的四种方法。此类修饰可增强材料的预期性能,这可能在药物递送、细胞培养、电子学和组织工程等高科技领域带来重大进展。

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