Agreda-Castañeda Fernando, Freixa-Sala Roger, Franco Marco, Bultó-Gonzalvo Ramón, Areal-Calama Joan
Hospital Universitari Germans Trias I Pujol [Germans Trias I Pujol University Hospital], Barcelona, Spain.
World J Urol. 2024 May 2;42(1):281. doi: 10.1007/s00345-024-04984-5.
The analysis of post-HoLEP urinary incontinence (UI) has traditionally focused on stress UI. Our aim is to evaluate the factors associated with stress and urgency UI in the first month after the surgery.
Data were obtained from patients who underwent HoLEP by the same experienced surgeon. UI was evaluated at one month and at 6 months after the surgery. Three groups were defined: continent patients, patients with pure urgency UI and patients with stress or mixed UI. Preoperative, intraoperative, urodynamic and clinical variables were analyzed and compared between the three groups.
In total, 235 subjects were included. One month after the surgery, 156 (66.5%) were continent (group 1), 49 (20.8%) reported pure urgency UI (group 2), and 30 (12.7%) reported some level of stress UI (group 3). In Group 2, the factors associated with urgency UI in the univariate analysis were age, presurgical urgency UI, having diabetes or hypertension. In Group 3, age, prostatic volume, preoperative PSA, time of enucleation, weight of the resection in grams, having an IDC or being diabetic were significant in the univariate analysis. In the multivariate analysis, age predicts both types of UI, while prostatic volume and having an IDC predict stress or mixed UI.
In the first month post-HoLEP, age is a predictive factor of urgency UI and stress UI. In addition, prostatic volume and the presence of an indwelling urinary catheter are predictive factors of stress UI.
传统上,经尿道前列腺剜除术(HoLEP)后尿失禁(UI)的分析主要集中在压力性尿失禁上。我们的目的是评估手术后第一个月与压力性和急迫性尿失禁相关的因素。
数据来自由同一位经验丰富的外科医生进行HoLEP手术的患者。在术后1个月和6个月对尿失禁进行评估。定义了三组:尿控正常的患者、单纯急迫性尿失禁患者以及压力性或混合性尿失禁患者。对三组患者的术前、术中、尿动力学和临床变量进行分析和比较。
总共纳入了235名受试者。术后1个月,156名(66.5%)患者尿控正常(第1组),49名(20.8%)报告有单纯急迫性尿失禁(第2组),30名(12.7%)报告有一定程度的压力性尿失禁(第3组)。在第2组中,单因素分析中与急迫性尿失禁相关的因素有年龄、术前急迫性尿失禁、患有糖尿病或高血压。在第3组中,年龄、前列腺体积、术前前列腺特异性抗原(PSA)、剜除时间、切除重量(克)、患有原位癌或糖尿病在单因素分析中具有显著性。多因素分析中,年龄可预测两种类型的尿失禁,而前列腺体积和患有原位癌可预测压力性或混合性尿失禁。
在HoLEP术后第一个月,年龄是急迫性尿失禁和压力性尿失禁的预测因素。此外,前列腺体积和留置导尿管是压力性尿失禁的预测因素。