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儿童热性惊厥的发病率在 SARS-CoV-2 大流行期间是否发生了变化?

Has the Incidence of Febrile Convulsions in Childhood Changed During the SARS-CoV-2 Pandemic?

机构信息

Faculty of Medicine, Department of Pediatrics, University of Pecs, Pecs, Hungary.

Faculty of Medicine, Institute of Bioanalysis, University of Pecs, Pecs, Hungary.

出版信息

J Child Neurol. 2024 May;39(5-6):190-194. doi: 10.1177/08830738241249630. Epub 2024 May 2.

DOI:10.1177/08830738241249630
PMID:38698642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11179305/
Abstract

SARS-CoV-2 infection in children is usually asymptomatic or only mild symptoms are typical. The aim of our study was to assess the incidence of febrile convulsions in our own patients with COVID-19. In our retrospective study, we reviewed the data of children who presented at our University Hospital from March 2020 to March 2022 with febrile convulsion. The control group were children admitted to the hospital because of febrile convulsions from January 2018 to January 2020. During the coronavirus pandemic, 51 patients were examined with febrile convulsions. The majority (86.3%) of children had their first febrile convulsion during this period. We diagnosed simple febrile convulsions in 40 cases and complicated ones in 11 cases. The family history of febrile convulsion or epilepsy was present in 12 (23.5%) patients. In addition to febrile convulsion, SARS-CoV-2 infection was confirmed by laboratory testing in 4 cases (7.8%). Three of them had febrile convulsion during the Omicron variant period. During the coronavirus pandemic, the number of children examined because of having febrile convulsions was not higher than in the control period. The coronavirus is unlikely to increase the risk of febrile convulsions.

摘要

儿童感染 SARS-CoV-2 通常无症状或仅有轻度症状。我们的研究目的是评估 COVID-19 患儿中热性惊厥的发生率。在我们的回顾性研究中,我们回顾了 2020 年 3 月至 2022 年 3 月期间因热性惊厥在我院就诊的患儿数据。对照组为 2018 年 1 月至 2020 年 1 月期间因热性惊厥入院的患儿。在冠状病毒大流行期间,有 51 例热性惊厥患儿接受了检查。在此期间,大多数(86.3%)患儿首次发生热性惊厥。我们诊断单纯性热性惊厥 40 例,复杂性热性惊厥 11 例。12 例(23.5%)患儿有热性惊厥或癫痫家族史。除热性惊厥外,实验室检查还确诊了 4 例(7.8%)SARS-CoV-2 感染。其中 3 例发生在奥密克戎变异株流行期间。在冠状病毒大流行期间,因热性惊厥接受检查的患儿数量并未高于对照期间。冠状病毒不太可能增加热性惊厥的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c95/11179305/bf927bb1471a/10.1177_08830738241249630-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c95/11179305/bf927bb1471a/10.1177_08830738241249630-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c95/11179305/bf927bb1471a/10.1177_08830738241249630-fig1.jpg

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本文引用的文献

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The Impact of Omicron Wave on Pediatric Febrile Seizure.奥密克戎变异株流行对儿童热性惊厥的影响
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Pediatrics. 2022 Nov 1;150(5). doi: 10.1542/peds.2022-058167.
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