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食管裂孔疝患者行裂孔修补和胃固定术而不行抗反流手术的功能结果。

Functional results after hiatal repair and gastropexy without fundoplication in patients with paraoesophageal hernia.

机构信息

Department of Visceral Surgery, Faculty of Biology and Medicine UNIL, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011, Lausanne, Switzerland.

Department of Gastroenterology and Hepatology, Faculty of Biology and Medicine UNIL, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011, Lausanne, Switzerland.

出版信息

Langenbecks Arch Surg. 2024 May 3;409(1):150. doi: 10.1007/s00423-024-03340-w.

Abstract

PURPOSE

Paraoesophageal hernias (PEH) are associated with a high complication rate and often occur in elderly and fragile patients. Surgical gastropexy without fundoplication is an accepted alternative procedure; however, outcomes and functional results are rarely described. Our study aims to evaluate short-term outcomes and the long-term quality of life after gastropexy as treatment for PEH.

METHODS

Single center cohort analysis of all consecutive patients who underwent gastropexy for PEH without fundoplication. Postoperative outcomes and functional results were retrospectively collected. Reflux symptoms developed postoperatively were reported using the validated quality of life questionnaire: GERD-Health Related Quality of Life Qestionnaire (GERD-HRQL).

RESULTS

Thirty patients (median age: 72 years (65-80)) were included, 40% classified as ASA III. Main PEH symptoms were reflux (63%), abdominal/thoracic pain (47%), pyrosis (33%), anorexia (30%), and food blockage (26%). Twenty-six laparoscopies were performed (86%). Major complications (III-IVb) occurred in 9 patients (30%). Seven patients (23%) had PEH recurrence, all re-operated, performing a new gastropexy. Median follow-up was 38 (17-50) months. Twenty-two patients (75%) reported symptoms resolution with median GERD-HRQL scale of 4 (1-6). 72% (n = 21) reported operation satisfaction. GERD-HRQL was comparable between patients who were re-operated for recurrence and others: 5 (2-19) versus 3 (0-6), p = 0.100.

CONCLUSION

Gastropexy without fundoplication was performed by laparoscopy in most cases with acceptable complications rates. Two-thirds of patients reported symptoms resolution, and long-term quality-of-live associated to reflux symptoms is good. Although the rate of PEH recurrence requiring a new re-intervention remained increased (23%), it does not seem to affect long-term functional results.

摘要

目的

膈疝(PEH)与高并发症发生率相关,常发生于老年和脆弱患者中。不进行胃底折叠术的膈疝修补术是一种被接受的替代手术方法;然而,术后结果和功能结果很少被描述。我们的研究旨在评估膈疝修补术治疗 PEH 的短期结果和长期生活质量。

方法

对所有连续接受膈疝修补术(不进行胃底折叠术)治疗的患者进行单中心队列分析。回顾性收集术后结果和功能结果。术后出现的反流症状采用经过验证的生活质量问卷:反流相关性健康相关生活质量问卷(GERD-HRQL)进行报告。

结果

共纳入 30 例患者(中位年龄:72 岁(65-80 岁)),40%为 ASA III 级。主要的 PEH 症状是反流(63%)、腹部/胸部疼痛(47%)、烧心(33%)、食欲不振(30%)和食物堵塞感(26%)。26 例采用腹腔镜手术(86%)。9 例(30%)发生主要并发症(III-IVb 级)。7 例(23%)患者出现 PEH 复发,均再次手术,行新的膈疝修补术。中位随访时间为 38(17-50)个月。22 例(75%)患者报告症状缓解,中位 GERD-HRQL 评分为 4(1-6)。72%(n=21)患者对手术满意。复发和未复发患者的 GERD-HRQL 评分相似:5(2-19)与 3(0-6),p=0.100。

结论

大多数情况下,腹腔镜膈疝修补术可采用不进行胃底折叠术的方法进行,并发症发生率可接受。三分之二的患者报告症状缓解,与反流症状相关的长期生活质量良好。尽管需要新的再次干预的 PEH 复发率仍然较高(23%),但似乎不会影响长期功能结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc81/11068662/b6d819109337/423_2024_3340_Fig1_HTML.jpg

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