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大麻二酚抗肿瘤作用机制的研究进展。

Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol.

机构信息

Department of Immunology, School of Basic Medical Sciences, Binzhou Medical University, Yantai 264003, China.

Department of Edible Mushrooms, School of Agriculture, Ludong University, Yantai 264025, China.

出版信息

Molecules. 2024 Apr 24;29(9):1943. doi: 10.3390/molecules29091943.

Abstract

Cannabidiol (CBD), a non-psychoactive ingredient extracted from the hemp plant, has shown therapeutic effects in a variety of diseases, including anxiety, nervous system disorders, inflammation, and tumors. CBD can exert its antitumor effect by regulating the cell cycle, inducing tumor cell apoptosis and autophagy, and inhibiting tumor cell invasion, migration, and angiogenesis. This article reviews the proposed antitumor mechanisms of CBD, aiming to provide references for the clinical treatment of tumor diseases and the rational use of CBD.

摘要

大麻二酚(CBD)是从大麻植物中提取的一种非精神活性成分,已在多种疾病中显示出治疗效果,包括焦虑、神经系统疾病、炎症和肿瘤。CBD 通过调节细胞周期、诱导肿瘤细胞凋亡和自噬以及抑制肿瘤细胞侵袭、迁移和血管生成来发挥其抗肿瘤作用。本文综述了 CBD 的抗肿瘤作用机制,旨在为肿瘤疾病的临床治疗和 CBD 的合理应用提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffa3/11085351/d5da649d40b7/molecules-29-01943-g001.jpg

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