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韩国成年人年龄相关性眼病与近视和营养素的关系:一项横断面 KNHANES 研究。

Myopia and Nutrient Associations with Age-Related Eye Diseases in Korean Adults: A Cross-Sectional KNHANES Study.

机构信息

Department of Visual Optics, Far East University, Eumseong 27601, Republic of Korea.

Department of Food and Nutrition, Sahmyook University, Seoul 01795, Republic of Korea.

出版信息

Nutrients. 2024 Apr 25;16(9):1276. doi: 10.3390/nu16091276.

Abstract

This study assessed the prevalence of myopia, cataracts, glaucoma, and macular degeneration among Koreans over 40, utilizing data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES VII, 2018). We analyzed 204,973 adults (44% men, 56% women; mean age 58.70 ± 10.75 years), exploring the association between myopia and these eye diseases through multivariate logistic regression, adjusting for confounders and calculating adjusted odds ratios (ORs) with 95% confidence intervals (CIs). Results showed a myopia prevalence of 44.6%, cataracts at 19.4%, macular degeneration at 16.2%, and glaucoma at 2.3%, with significant differences across ages and genders. A potential link was found between myopia and an increased risk of cataracts and macular degeneration, but not with glaucoma. Additionally, a higher dietary intake of carbohydrates, polyunsaturated and n-6 fatty acids, vitamins, and minerals correlated with lower risks of these diseases, underscoring the importance of the diet in managing and preventing age-related eye conditions. These findings highlight the need for dietary considerations in public health strategies and confirm myopia as a significant risk factor for specific eye diseases in the aging Korean population.

摘要

本研究利用 2018 年第七次韩国国家健康与营养调查(KNHANES VII)的数据,评估了韩国 40 岁以上人群中近视、白内障、青光眼和黄斑变性的患病率。我们分析了 204973 名成年人(44%为男性,56%为女性;平均年龄 58.70±10.75 岁),通过多变量逻辑回归探讨了近视与这些眼部疾病之间的关系,调整了混杂因素,并计算了调整后的优势比(OR)及其 95%置信区间(CI)。结果显示,近视患病率为 44.6%,白内障为 19.4%,黄斑变性为 16.2%,青光眼为 2.3%,且在不同年龄和性别之间存在显著差异。研究发现近视与白内障和黄斑变性风险增加之间存在潜在联系,但与青光眼无关。此外,较高的碳水化合物、多不饱和和 n-6 脂肪酸、维生素和矿物质的饮食摄入与这些疾病的风险降低相关,这强调了饮食在管理和预防与年龄相关的眼部疾病中的重要性。这些发现强调了在公共卫生策略中考虑饮食的必要性,并证实了近视是韩国老年人群体中特定眼部疾病的重要危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c29/11085160/23dea709ac75/nutrients-16-01276-g001.jpg

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