Schulthess H K, Häcki W H
Schweiz Med Wochenschr. 1985 Apr 27;115(17):582-6.
Injection sclerotherapy of esophageal varices is now firmly established. The indication and results are exemplified by the experience gained during the last 5 1/2 years at our institution. The early mortality rate within 30 days was 20% for patients needing emergency sclerotherapy during acute bleeding, and 4.4% for all other patients. The cumulative two-year survival rate of all patients was 54%. Further hemorrhage occurred in 4.8% per patient-month, mostly within the first year. Every acute esophageal hemorrhage should be treated with injection sclerotherapy. Repetition of this procedure reduces the risk of rebleeding. The indication for prophylactic sclerotherapy prior to first bleeding is not yet clearly defined. However, patients with increased risk of bleeding should have the benefit of injection sclerotherapy.
食管静脉曲张的注射硬化疗法现已得到确立。我们机构过去5年半的经验说明了其适应证和治疗结果。急性出血期间需要急诊硬化疗法的患者30天内的早期死亡率为20%,其他所有患者为4.4%。所有患者的累积两年生存率为54%。每位患者每月再出血发生率为4.8%,大多发生在第一年。每次急性食管出血均应采用注射硬化疗法治疗。重复该操作可降低再出血风险。首次出血前预防性硬化疗法的适应证尚未明确界定。然而,出血风险增加的患者应能从注射硬化疗法中获益。