Department of Rheumatology and Immunology, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Department of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Clin Rheumatol. 2024 Jul;43(7):2343-2349. doi: 10.1007/s10067-024-07003-5. Epub 2024 May 15.
The patient presented to the clinic with painful muscle swelling in the right lower extremity, which improved with immunosuppressive therapy. Initially, the condition was diagnosed as polymyositis but recurred soon after. After imaging and biopsy, the final diagnosis was primary skeletal muscle peripheral T-cell lymphoma, not otherwise specified (PSM-PTCL, NOS). In this report, we discuss the challenges in diagnosing and treating this aggressive malignancy and review the literature on PSM-PTCL, NOS. Key Points • To date, there are few reports of PSM-PTCL, NOS, and our case is the tenth. • It is crucial to consider PSM-PTCL, NOS, when presenting with localized muscle edema and unexplained pain. • Histopathological examination is likely the most effective method for diagnosing this rare disease.
患者因右下肢肌肉肿胀伴疼痛就诊于诊所，经免疫抑制治疗后症状改善。最初诊断为多发性肌炎，但很快复发。经过影像学和活检，最终诊断为原发性骨骼肌外周 T 细胞淋巴瘤，非特指型（PSM-PTCL，NOS）。本报告讨论了诊断和治疗这种侵袭性恶性肿瘤的挑战，并复习了 PSM-PTCL，NOS 的文献。
关键点
• 迄今为止，PSM-PTCL，NOS 的报道较少，本病例为第十例。
• 当出现局部肌肉水肿和不明原因疼痛时，必须考虑 PSM-PTCL，NOS。
• 组织病理学检查可能是诊断这种罕见疾病最有效的方法。
