Rasch 验证在西班牙圆锥角膜患者中使用的圆锥角膜终点评估问卷。

Rasch validation of the Keratoconus End-Points Assessment Questionnaire in a Spanish population with keratoconus.

机构信息

Práctica Privada, Medellín, Colombia; The affiliation of K. Balparda, L. García-Onrubia, and F.J. Valentín-Bravo at the time of this article was the Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

Fundación Jiménez Díaz, Madrid, Spain; The affiliation of K. Balparda, L. García-Onrubia, and F.J. Valentín-Bravo at the time of this article was the Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

出版信息

Arch Soc Esp Oftalmol (Engl Ed). 2024 Aug;99(8):323-330. doi: 10.1016/j.oftale.2024.05.006. Epub 2024 May 19.

DOI:10.1016/j.oftale.2024.05.006

PMID:38768852

Abstract

OBJECTIVE

To carry out a methodologically complete validation of the Spanish version of the Keratoconus End-Points Assessment Questionnaire (KEPAQ) in a Spanish population with keratoconus.

METHODS

Analytical, prospective study, including patients with keratoconus without previous surgical history, in which a measurement of quality of life was performed using the KEPAQ questionnaire, a complete exploration of the anterior pole and a corneal elevation topography with the Galilei G6 topographer. The evaluation of the psychometric characteristics of the scale in the studied population was carried out using Rasch modeling.

RESULTS

A total of 140 patients with keratoconus were included, with a median age of 26.0 years, the majority (57.6%) being men. For the KEPAQ-E subscale, the median score was 69.3, with a reliability of 0.85 and an eigenvalue of the first contrast of 2.34. For the KEPAQ-F, the median score was 56.4, with a reliability of 0.88 and an eigenvalue of 2.00. All infit and outfit parameters were within normal limits for both subscales. A significant evaluation was found between the evaluations of both subscales (rho = 0.696; p < 0.001). The evaluations of the subscales and various clinical and tomographic characteristics showed a significant classification between them (p value between 0.048 y 0.001).

CONCLUSION

The KEPAQ is a psychometrically robust and valid scale to evaluate quality of life in the Spanish population with keratoconus. This questionnaire can be easily used for both clinical and research aims.

摘要

目的

在西班牙圆锥角膜患者中，对圆锥角膜终点评估问卷（KEPAQ）的西班牙语版本进行方法学上完整的验证。

方法

分析性、前瞻性研究，纳入无既往手术史的圆锥角膜患者，使用 KEPAQ 问卷对其进行生活质量评估，对前极进行全面检查，并使用 Galilei G6 地形图仪进行角膜高度测量。使用 Rasch 模型对研究人群中量表的心理测量特性进行评估。

结果

共纳入 140 例圆锥角膜患者，中位年龄为 26.0 岁，大多数（57.6%）为男性。KEPAQ-E 子量表的中位数评分为 69.3，可靠性为 0.85，第一对比特征值为 2.34。KEPAQ-F 的中位数评分为 56.4，可靠性为 0.88，特征值为 2.00。两个子量表的所有 infit 和 outfit 参数均在正常范围内。两个子量表的评估之间存在显著差异（rho=0.696;p<0.001）。子量表的评估以及各种临床和断层扫描特征之间存在显著的分类（p 值在 0.048 至 0.001 之间）。