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主要豆类蛋白源生物活性化合物对人和动物健康影响的综述

A Review of Bioactive Compound Effects from Primary Legume Protein Sources in Human and Animal Health.

作者信息

Shea Zachary, Ogando do Granja Matheus, Fletcher Elizabeth B, Zheng Yaojie, Bewick Patrick, Wang Zhibo, Singer William M, Zhang Bo

机构信息

United States Department of Agriculture-Agricultural Research Service, Raleigh Agricultural Research Station, Raleigh, NC 27606, USA.

School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.

出版信息

Curr Issues Mol Biol. 2024 May 1;46(5):4203-4233. doi: 10.3390/cimb46050257.

Abstract

The global demand for sustainable and nutritious food sources has catalyzed interest in legumes, known for their rich repertoire of health-promoting compounds. This review delves into the diverse array of bioactive peptides, protein subunits, isoflavones, antinutritional factors, and saponins found in the primary legume protein sources-soybeans, peas, chickpeas, and mung beans. The current state of research on these compounds is critically evaluated, with an emphasis on the potential health benefits, ranging from antioxidant and anticancer properties to the management of chronic diseases such as diabetes and hypertension. The extensively studied soybean is highlighted and the relatively unexplored potential of other legumes is also included, pointing to a significant, underutilized resource for developing health-enhancing foods. The review advocates for future interdisciplinary research to further unravel the mechanisms of action of these bioactive compounds and to explore their synergistic effects. The ultimate goal is to leverage the full spectrum of benefits offered by legumes, not only to advance human health but also to contribute to the sustainability of food systems. By providing a comprehensive overview of the nutraceutical potential of legumes, this manuscript sets a foundation for future investigations aimed at optimizing the use of legumes in the global pursuit of health and nutritional security.

摘要

全球对可持续且营养丰富的食物来源的需求激发了人们对豆类的兴趣,豆类以其丰富的促进健康的化合物而闻名。本综述深入探讨了主要豆类蛋白质来源——大豆、豌豆、鹰嘴豆和绿豆中发现的各种生物活性肽、蛋白质亚基、异黄酮、抗营养因子和皂苷。对这些化合物的当前研究状况进行了批判性评估,重点关注其潜在的健康益处,从抗氧化和抗癌特性到糖尿病和高血压等慢性疾病的管理。文中突出了经过广泛研究的大豆,并纳入了其他豆类相对未被探索的潜力,指出这是开发有益健康食品的重要但未充分利用的资源。该综述倡导未来开展跨学科研究,以进一步阐明这些生物活性化合物的作用机制,并探索它们的协同效应。最终目标是充分利用豆类提供的全方位益处,不仅促进人类健康,还为食品系统的可持续性做出贡献。通过全面概述豆类的营养保健潜力,本手稿为未来旨在优化豆类在全球健康和营养安全追求中的应用的研究奠定了基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c4a/11120442/7efc26e05ff0/cimb-46-00257-g001.jpg

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