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后生元作为代谢物及其生物治疗潜力。

Postbiotics as Metabolites and Their Biotherapeutic Potential.

机构信息

Center of Clinical and Preclinical Research MEDIPARK, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Trieda SNP 1, 040 11 Košice, Slovakia.

出版信息

Int J Mol Sci. 2024 May 16;25(10):5441. doi: 10.3390/ijms25105441.

Abstract

This review highlights the role of postbiotics, which may provide an underappreciated avenue doe promising therapeutic alternatives. The discovery of natural compounds obtained from microorganisms needs to be investigated in the future in terms of their effects on various metabolic disorders and molecular pathways, as well as modulation of the immune system and intestinal microbiota in children and adults. However, further studies and efforts are needed to evaluate and describe new postbiotics. This review provides available knowledge that may assist future research in identifying new postbiotics and uncovering additional mechanisms to combat metabolic diseases.

摘要

本综述强调了后生元的作用,后生元可能为有前景的治疗替代品提供了一条尚未被充分认识的途径。未来需要研究从微生物中获得的天然化合物对各种代谢紊乱和分子途径的影响,以及对儿童和成人免疫系统和肠道微生物群的调节作用。然而,需要进一步的研究和努力来评估和描述新的后生元。本综述提供了现有知识,可能有助于未来的研究,以确定新的后生元并发现更多对抗代谢疾病的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04bc/11121590/4890dbbe0386/ijms-25-05441-g001.jpg

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