Faculty of Chemistry, Warsaw University of Technology, Koszykowa 75 Street, 00-662 Warsaw, Poland.
Department of Genetic Engineering, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3 Street, 05-110 Jabłonna, Poland.
Int J Mol Sci. 2024 May 18;25(10):5510. doi: 10.3390/ijms25105510.
Post-fermentation wastes are rich sources of various biologically active compounds with antimicrobial activity, whose potential is not being fully exploited. One of the possible applications of post-fermentation waste may be its use as a natural preservative that effectively combats pathogens found in formulations. The study aims included the following: (1) compare the antimicrobial and antioxidant activity of fermented vegetable extracts (FVEs), (2) examine the inhibition of cosmetic-borne pathogens by FVEs, and (3) estimate the preservative effectiveness of FVEs in o/w emulsions. It was found that fermented white cabbage, cucumber, celery, and the mixture of fermented white cabbage, cucumber, and celery (1:1:1) showed antibacterial and antifungal activity against all the tested reference microbial strains. The addition of fermented cucumber, celery, and the mixture of fermented white cabbage, cucumber, and celery (1:1:1) to the o/w emulsion fulfilled criterion A of the preservative effectiveness test for , , and , but did not fulfill the criterion for and . The tested FVEs have comparable activity to inhibit pathogens in o/w emulsion as sodium benzoate. The results of our study prove that FVEs can be valuable raw materials supporting the preservative system, which, in turn, can significantly reduce the concentration of preservatives used in o/w emulsion.
发酵后的废物是含有各种具有抗菌活性的生物活性化合物的丰富来源,但这些潜在的化合物尚未得到充分利用。发酵后废物的一种可能应用是将其用作天然防腐剂,有效对抗配方中发现的病原体。本研究的目的包括:(1)比较发酵蔬菜提取物(FVEs)的抗菌和抗氧化活性,(2)研究 FVEs 对化妆品携带病原体的抑制作用,(3)评估 FVEs 在 o/w 乳液中的防腐效果。研究发现,发酵的白菜、黄瓜、芹菜以及发酵的白菜、黄瓜和芹菜(1:1:1)混合物对所有测试的参考微生物菌株均具有抗菌和抗真菌活性。向 o/w 乳液中添加发酵的黄瓜、芹菜以及发酵的白菜、黄瓜和芹菜(1:1:1)混合物,符合防腐剂有效性测试针对 、 、 和 的标准 A,但不符合 和 的标准。测试的 FVEs 在抑制 o/w 乳液中的病原体方面与苯甲酸钠具有相当的活性。我们的研究结果证明,FVEs 可以成为支持防腐剂体系的有价值的原料,从而可以显著降低 o/w 乳液中防腐剂的浓度。