Department of Neurology, Lithuanian University of Health Sciences, A. Mickevičiaus Str. 9, LT-44307 Kaunas, Lithuania.
Department of Radiology, Lithuanian University of Health Sciences, A. Mickevičiaus Str. 9, LT-44307 Kaunas, Lithuania.
Medicina (Kaunas). 2024 May 6;60(5):768. doi: 10.3390/medicina60050768.
: while acute ischemic stroke is the leading cause of epilepsy in the elderly population, data about its risk factors have been conflicting. Therefore, the aim of our study is to determine the association of early and late epileptic seizures after acute ischemic stroke with cerebral cortical involvement and electroencephalographic changes. : a prospective cohort study in the Hospital of the Lithuanian University of Health Sciences Kaunas Clinics Department of Neurology was conducted and enrolled 376 acute ischemic stroke patients. Data about the demographical, clinical, radiological, and encephalographic changes was gathered. Patients were followed for 1 year after stroke and assessed for late ES. : the incidence of ES was 4.5%, the incidence of early ES was 2.7% and the incidence of late ES was 2.4%. The occurrence of early ES increased the probability of developing late ES. There was no association between acute cerebral cortical damage and the occurrence of ES, including both early and late ES. However, interictal epileptiform discharges were associated with the occurrence of ES, including both early and late ES.
急性缺血性脑卒中是老年人癫痫的主要病因,但关于其危险因素的数据一直存在争议。因此,我们的研究旨在确定急性缺血性脑卒中后早期和晚期癫痫发作与大脑皮质受累和脑电图变化的关系。在立陶宛健康科学大学考纳斯临床医学院神经科进行了一项前瞻性队列研究,共纳入 376 例急性缺血性脑卒中患者。收集了人口统计学、临床、影像学和脑电图变化的数据。对患者进行了卒中后 1 年的随访,并评估了晚期癫痫发作。癫痫发作的发生率为 4.5%,早期癫痫发作的发生率为 2.7%,晚期癫痫发作的发生率为 2.4%。早期癫痫发作的发生增加了晚期癫痫发作的可能性。急性大脑皮质损伤与癫痫发作(包括早期和晚期癫痫发作)之间无相关性。然而,发作间期癫痫样放电与癫痫发作(包括早期和晚期癫痫发作)有关。