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股骨颈前倾角改变对采用PFNA固定的转子间骨折稳定性的力学影响:有限元分析

Mechanical effect of changed femoral neck ante-version angles on the stability of an intertrochanteric fracture fixed with PFNA: A finite element analysis.

作者信息

Li Song-Jian, Huang Hua-Jian, Li Chen-Tian, Hu Guo-Ju, Yu Fei, Liu Yu-Bin

机构信息

Orthopedics Center, Department of Orthopedics and Traumatology, Zhujiang Hospital, Southern Medical University, China.

College of Management, Guangdong Polytechnic Normal University, China.

出版信息

Heliyon. 2024 May 17;10(10):e31480. doi: 10.1016/j.heliyon.2024.e31480. eCollection 2024 May 30.

Abstract

OBJECTIVE

Change of femoral neck ante-version angle postoperatively due to inadequate reduction could result in unsatisfying treatment outcome of intertrochanteric fracture. However, the influence of increased or decreased femoral neck ante-version on the biomechanical stability of the bone-implant complex has rarely been studied.

METHODS

A finite element model of a complete normal human femur with normal femoral neck ante-version as 13° was established accurately by scanning a 64 year old female femur. The models of 31-A1.1 intertrochanteric fractures with different femoral neck ante-version angles of 3°, 5.5°, 8°, 10.5°, 13°, 15.5°, 18°, 20.5°, 23° were created. They were assembled with a proximal femoral nail anti-rotation (PFNA) device. The biomechanical differences with varying femoral neck ante-version angles were compared using finite element analysis method.

RESULTS

As the femoral neck ante-version angle gradually increased from 13° to 23°with a gradient of 2.5°, the peak von Mises stress was gradually increased from 137.82 MPa to 276.02 MPa. Similarly, the peak von Mises stress was gradually increased from 137.82 MPa to 360.12 MPa with the femoral neck ante-version angle decreased from 13° to 3°. When decreased ante-version angle of 7.5° and increased ante-version angle of 10° will exceed the yield strength of femoral (240.32 MPa), the risk of femoral fracture will increase significantly. The maximum displacement of the femur was significantly reduced for increased ante-version models than for decreased ante-version models, whether the changes of ante-version angles were 2.5°, 5°, 7.5° or 10°. he maximum stress of PFNA was found in the intersection of main nail and helical blade, and became greater gradually as the ante-version angle increased or decreased with a gradient of 2.5°. The maximum stress of PFNA was presented in the model 5.5° with the maximum stress of 724.42 MPa (near to the yield strength of titanium alloy of 700-1000 MPa), producing the breakage risk of PFNA. The maximum displacement of the PFNA was significantly reduced for increased ante-version models than for decreased ante-version models, whether the changes of ante-version angles were 2.5°, 5°, 7.5° or 10°.

CONCLUSION

Based on the results of present study, it was demonstrated that the anatomical reduction of femoral neck ante-version was vital to secure the optimal stability. Abnormal femoral ante-version could increase the potential risk of failure for intertrochanteric fracture after PFNA. The stability of increased femoral ante-version (less than 10°) was superior to the stability of decreased ante-version (less than 5°) for the cases of difficulty to acquire anatomical reduction. The clinical implication of the finding was that increased femoral neck ante-version had an advantage of mechanical stability towards the decreased femoral neck ante-version for the cases of comminuted intertrochanteric fracture and failure of anatomical reduction.

摘要

目的

股骨颈前倾角术后复位不当可导致股骨转子间骨折治疗效果不佳。然而,股骨颈前倾角增大或减小对骨 - 植入物复合体生物力学稳定性的影响鲜有研究。

方法

通过扫描一名64岁女性股骨,精确建立正常股骨颈前倾角为13°的完整正常人体股骨有限元模型。创建31 - A1.1型股骨转子间骨折且股骨颈前倾角分别为3°、5.5°、8°、10.5°、13°、15.5°、18°、20.5°、23°的模型。将其与股骨近端抗旋髓内钉(PFNA)装置组装。采用有限元分析方法比较不同股骨颈前倾角时的生物力学差异。

结果

随着股骨颈前倾角以2.5°为梯度从13°逐渐增至23°,冯·米塞斯应力峰值从137.82MPa逐渐增至276.02MPa。同样,随着股骨颈前倾角从13°降至3°,冯·米塞斯应力峰值从137.82MPa逐渐增至360.12MPa。当股骨前倾角减小7.5°且增大10°时将超过股骨屈服强度(240.32MPa),股骨骨折风险将显著增加。无论前倾角变化为2.5°、5°、7.5°还是10°,股骨前倾角增大模型的股骨最大位移均显著小于前倾角减小模型。PFNA的最大应力出现在主钉与螺旋刀片的交汇处,且随着前倾角以2.5°为梯度增大或减小而逐渐增大。PFNA最大应力出现在5.5°模型中,最大应力为724.42MPa(接近钛合金屈服强度700 - 1000MPa),存在PFNA断裂风险。无论前倾角变化为2.5°、5°、7.5°还是10°,股骨前倾角增大模型的PFNA最大位移均显著小于前倾角减小模型。

结论

基于本研究结果表明,股骨颈前倾角解剖复位对于确保最佳稳定性至关重要。股骨前倾角异常会增加PFNA术后股骨转子间骨折失败的潜在风险。对于难以获得解剖复位的病例,股骨前倾角增大(小于10°)的稳定性优于前倾角减小(小于5°)。该研究结果的临床意义在于,对于粉碎性股骨转子间骨折及解剖复位失败的病例,股骨颈前倾角增大在力学稳定性方面优于股骨颈前倾角减小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1ba/11133928/dcafa90561a2/gr1.jpg

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