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输尿管镜检查及积极的结石治疗在八旬老人中是否安全有效?当前文献综述。

Is ureteroscopy and active stone treatment safe and effective in octogenarians? A review of current literature.

作者信息

Bhatnagar Daksh, Nedbal Carlotta, Somani Bhaskar Kumar

机构信息

Department of Medical, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

出版信息

Arab J Urol. 2024 Feb 19;22(3):171-178. doi: 10.1080/20905998.2024.2320028. eCollection 2024.

Abstract

BACKGROUND

With the aging of our patient population, and the increasing incidence of kidney stone disease in the elderly, active stone treatment is becoming more common. In this review of current literature, we aim to assess safety and efficacy of ureteroscopy (URS) as primary treatment for urolithiasis in the octogenarians.

MATERIALS AND METHODS

A scoping review of literature according to the PRISMA guidelines was performed, using the relevant search terms. Original articles were screened and included. A narrative review of the studies is provided, with emphasis on outcomes of URS in the elderly.

RESULTS

10 studies were included in the analysis. URS performed in the elderly population showed a good safety and efficacy, with stone-free rates (SFR) comparable to the general population. URS specific complication rates seems to be comparable to the other age groups, with postoperative events mostly related to anaesthesia and pre-existing medical conditions. The overall complication rate was still low, with a slightly prolonged hospital stay. Predictors for SFR were age, severe comorbidities and stone burden.

CONCLUSION

URS for stone treatment in the elderly population is safe and effective, with comparable surgical outcomes to that of the general population. As comorbidities play an important role in the fitness for surgery and overall survival, risks and benefit of active stone treatment should be carefully balanced in this group.

摘要

背景

随着我们患者群体的老龄化,以及老年人肾结石疾病发病率的增加,积极的结石治疗变得越来越普遍。在本次对当前文献的综述中,我们旨在评估输尿管镜检查(URS)作为八旬老人尿路结石主要治疗方法的安全性和有效性。

材料与方法

根据PRISMA指南,使用相关检索词对文献进行范围综述。筛选并纳入原始文章。对这些研究进行叙述性综述,重点关注老年人URS的结果。

结果

10项研究纳入分析。在老年人群中进行的URS显示出良好的安全性和有效性,结石清除率(SFR)与一般人群相当。URS的特定并发症发生率似乎与其他年龄组相当,术后事件大多与麻醉和既往疾病有关。总体并发症发生率仍然较低,住院时间略有延长。SFR的预测因素为年龄、严重合并症和结石负荷。

结论

在老年人群中,URS治疗结石是安全有效的,手术结果与一般人群相当。由于合并症在手术适应性和总体生存中起着重要作用,对于这一群体,应仔细权衡积极结石治疗的风险和益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b656/11136461/e3ccbc57335e/TAJU_A_2320028_F0001_OC.jpg

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