一种实用的方法，用于使用基因组标准协会 MIxS 报告标准进行比较基因组学和宏基因组学。

A Practical Approach to Using the Genomic Standards Consortium MIxS Reporting Standard for Comparative Genomics and Metagenomics.

机构信息

Environmental Genomics and System Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.

Pacific Northwest National Laboratory, Richland, WA, USA.

出版信息

Methods Mol Biol. 2024;2802:587-609. doi: 10.1007/978-1-0716-3838-5_20.

DOI:10.1007/978-1-0716-3838-5_20

PMID:38819573

Abstract

Comparative analysis of (meta)genomes necessitates aggregation, integration, and synthesis of well-annotated data using standards. The Genomic Standards Consortium (GSC) collaborates with the research community to develop and maintain the Minimum Information about any (x) Sequence (MIxS) reporting standard for genomic data. To facilitate the use of the GSC's MIxS reporting standard, we provide a description of the structure and terminology, how to navigate ontologies for required terms in MIxS, and demonstrate practical usage through a soil metagenome example.

摘要

比较（宏）基因组分析需要使用标准对经过良好注释的数据进行聚合、整合和综合。基因组标准联盟（GSC）与研究界合作，开发和维护用于基因组数据的最低信息关于任何（x）序列（MIxS）报告标准。为了促进使用 GSC 的 MIxS 报告标准，我们提供了对结构和术语的描述，如何为 MIxS 中的必需术语导航本体，以及通过土壤宏基因组示例演示实际用法。